Table 2 Genotype and allele frequencies of the
Table 2. Genotype and allele frequencies of the CYP 24 A 1, CYP 27 B 1 and CYP 2 R 1 SNPs in the context of serum 25(OH)D 3 levels Gene CYP 24 A 1 CYP 27 B 1 CYP 2 R 1 SNPs Allele/Genotype rs 2762939 CC CG GG CC: CG+GG ≤ 50 nmol/L n=135 (%) 17 (12. 59) 55 (40. 74) 63 (46. 67) 17 (12. 59): 118 (87. 40) > 50 nmol/L n=27 (%) 0 (0. 00) 10 (37. 04) 17 (62. 96) 0 (0. 00): 27 (100. 00) GG: CC+CG C G rs 6013897 AA AT TT AA: AT+TT 63 (46. 67): 72 (53. 33) 89 (32. 96) 181 (67. 04) n=135 (%) 17 (12. 59) 53 (39. 25) 65 (48. 15) 17 (12. 60): 118 (87. 40) 17 (62. 96): 10 (37. 04) 10 (18. 52) 44 (81. 48) n=27 (%) 0 (0. 00) 9 (33. 33) 18 (66. 67) 0 (0. 00): 27 (100. 00) TT: AA+AT A T rs 10877012 GG GT TT GG: GT+TT TT: GG+GT G T rs 4646536 AA AG GG AA: AG+GG GG: AA+AG A G rs 10741657 AA AG GG AA: AG+GG 65 (48. 15): 70 (51. 85) 87 (32. 22) 183 (67. 78) n=136 (%) 77 (56. 62) 51 (37. 50) 8 (5. 88) 77 (56. 62): 59 (43. 38) 8 (5. 88): 128 (94. 12) 205 (75. 37) 67 (24. 63) n=135 (%) 71 (52. 59) 53 (39. 26) 11 (8. 15) 71 (52. 59): 64 (47. 41) 11 (8. 15): 124 (91. 85) 195 (72. 22) 75 (27. 78) n=131 (%) 10 (7. 64) 57 (43. 51) 64 (48. 85) 10 (7. 64): 121 (92. 36) 18 (66. 67): 9 (33. 33) 9 (16. 67) 45 (83. 33) n=27 (%) 24 (88. 89) 3 (11. 11) 0 (0. 00) 24 (88. 89): 3 (11. 11) 0 (0. 00): 27 (100. 00) 51 (94. 44) 3 (5. 56) n=27 (%) 20 (74. 08) 7 (25. 92) 0 (0. 00) 20 (74. 08): 7 (25. 92) 0 (0. 00): 27 (100. 00) 47 (82. 46) 7 (12. 96) n=25 (%) 2 (8. 00) 10 (40. 00) 13 (52. 00) 2 (8. 00): 23 (92. 00) GG: AA+AG A G 64 (48. 85): 67 (51. 15) 77 (29. 39) 185 (70. 61) 13 (52. 00): 12 (48. 00) 14 (28. 00) 36 (72. 00) OR [CI 95%] p-value 1 (Reference) 0. 15 [0. 008 -2. 71] 0. 10 [0. 006 -1. 81] 0. 12 [0. 007 -2. 11] 0. 084 0. 036* 0. 051 1. 94 [0. 82 -4. 55] 0. 122 0. 46 [0. 22 -0. 96] 0. 035* 1 (Reference) 0. 16 [0. 009 -2. 90] 0. 10 [0. 006 -1. 76] 0. 12 [0. 007 -2. 11] 0. 095 0. 033* 0. 051 2. 15 [0. 90 -5. 13] 0. 078 0. 42 [0. 19 -0. 89] 0. 022* 1 (Reference) 5. 29 [1. 51 -18. 51] 5. 37 [0. 29 -96. 51] 6. 13 [1. 76 -21. 33] 0. 27 [0. 01 -4. 90] 0. 004* 0. 118 0. 001* 0. 196 5. 55 [1. 67 -18. 38] 0. 001* 1 (Reference) 2. 13 [0. 84 -5. 41] 6. 59 [0. 37 -116. 73] 2. 57 [1. 02 -6. 49] 0. 19 [0. 01 -3. 44] 0. 105 0. 082 0. 040* 0. 124 2. 58 [1. 11 -5. 96] 0. 022* 1 (Reference) 1. 14 [0. 21 -5. 99] 0. 98 [0. 19 -5. 03] 1. 05 [0. 21 -5. 12] 0. 877 0. 985 0. 949 1. 13 [0. 48 -2. 67] 0. 773 0. 93 [0. 47 -1. 83] 0. 843 SNP: Single nucleotide polymorphism, n: number of individuals, OR: Odds ratio, CI: confidence intervals. OR [95% CI] was calculated by chi-squared-test. *Significant p-value < 0. 05. Fatme Al Anouti et al. Investigating the Association of Vitamin D Metabolism Genes CYP 2 R 1, CYP 24 A 1 and CYP 27 B 1 with Vitamin D Status in Young Adult Emiratis. Journal of Food and Nutrition Research, 2017, Vol. 5, No. 1, 15 -21. doi: 10. 12691/jfnr-5 -1 -3 © The Author(s) 2015. Published by Science and Education Publishing.
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