Systemic Messenger RNA Therapy as a Treatment for

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Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia Ding An, Jessica L.

Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia Ding An, Jessica L. Schneller, Andrea Frassetto, Shi Liang, Xuling Zhu, Ji-Sun Park, Matt Theisen, Sue-Jean Hong, Jenny Zhou, Rajendran, Becca Levy, Rebecca Howell, Gilles Besin, Vladimir Presnyak, Staci Sabnis, Kerry E. Murphy-Benenato, E. Sathyajith Kumarasinghe, Timothy Salerno, Cosmin Mihai, Christine M. Lukacs, Randy J. Chandler, Lin T. Guey, Charles P. Venditti, Paolo G. V. Martini Cell Reports Volume 21 Issue 12 Pages 3548 -3558 (December 2017) DOI: 10. 1016/j. celrep. 2017. 11. 081 Copyright © 2017 The Author(s) Terms and Conditions

Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081) Copyright ©

Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081) Copyright © 2017 The Author(s) Terms and Conditions

Figure 1 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081)

Figure 1 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081) Copyright © 2017 The Author(s) Terms and Conditions

Figure 2 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081)

Figure 2 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081) Copyright © 2017 The Author(s) Terms and Conditions

Figure 3 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081)

Figure 3 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081) Copyright © 2017 The Author(s) Terms and Conditions

Figure 4 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081)

Figure 4 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081) Copyright © 2017 The Author(s) Terms and Conditions

Figure 5 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081)

Figure 5 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081) Copyright © 2017 The Author(s) Terms and Conditions

Figure 6 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081)

Figure 6 Cell Reports 2017 213548 -3558 DOI: (10. 1016/j. celrep. 2017. 11. 081) Copyright © 2017 The Author(s) Terms and Conditions