Surgical Innovation Team MIT Obesity Defined Under Weight

Surgical Innovation Team MIT

Obesity Defined • Under Weight = BMI < 18. 5 • Healthy Weight = BMI 20 -25 • Overweight = BMI 25 -30 • Obese = BMI 30 -35 • Morbidly Obese = BMI 35 -40 with related co-morbidities = BMI > 40 Morbidly obese patients are candidates for Bariatric procedures

Obesity & metabolic health q. What causes obesity? INDIVIDUAL FACTORS ENVIRONMENTAL FACTORS Education System Finances & Funding Cognition & Addiction Genetics Sleep, Stress & Immunity Healthcar e & policy delivery Workplace & Business Culture Nutrition Exercise& activity & levels activity levels Hormones & Metabolism Food Policy & Production Community & Lifestyle Planning

Egypti Population 100 M (100%) Adult Population Age 18+ 61 M (61%) Juvenile Population Age <18 yrs. 38 M (38%) Overweight BMI 25 -29. 9 20. 1 M (33%) Normal/Under weight BMI <24. 9 24. 4 M (40%) Obese Class I BMI 30 -34. 9 10. 2 M (59 %) No/Other Comorbidity 6. 5 M (73. 7%) Senior Population Age 80+ 1 M (1%) Obese BMI > 30 17. 4 M (29%) Obese Class III BMI >40 Gross Indicated Prevalence 870 K K ( 5%) Obese Class II BMI 35 -39. 9 6. 4 M (37 %) w/ T 2 D Gross Indicated Prevalence 2. 6 M (26. 3%) Clinical Excl. 30% Economic Excl. 40 % Net Indicated Prevalence 1 M No Comorbidity 1. 2 M (20%) With Comorbidities Gross Indicated Prevalence 5. 1 M (80%) Clinical Excl. 30% Economic Excl. 40% Net Indicated Prevalence 365 K Clinical Excl. 30% Economic Excl. 40% Net Indicated Prevalence 2. 1 M 7

Obesity is a serious global and Egyptian health problem Every 1 in 10 adults are obese worldwide 80% of people with obesity suffer from 1 or more comorbidities Diabetes Coronary Artery Disease Dyslipidemia EVERY 1 in 3 Osteoarthritis Amputations are obese in Egypt Hypertension Renal Failure Sleep Apnea Cancer 25% of people with obesity suffer from Type-2 Diabetes <1% ~8% <1% ~12% of indicated patients receive obesity surgery worldwide 15% growth per year of obesity surgery specialty worldwide of Egyptian adult population have Type-2 Diabetes 10 years Reduced life expectancy for obese with BMI>40 $2 Trillion Annual global cost of obesity of indicated patients receive obesity surgery in Egypt growth per year of obesity surgery specialty in Egypt

SURGICAL PROCEDURES SLEEVE GASTRECTOMY GASTRIC BYPASS MINI GASTRIC BYPASS BAND

OMH 4 GLOBAL MARKET LEAD TO UNDER-DEVELOPED MARKET WITH LOW PENETRATION RATE IN CEMA BARRIERS OMH GLOBAL BARRIERS 1 LOW PENETRATION RATE 2 TREMENDOUS SOCIAL PERCEIVED STIGMA & LACK OF INVASIVENESS OF AWARENESS WITH OBESITY SURGERY Disconnect between non-acute Low awareness of the full risks of condition and the perceived obesity and reluctance to treat it risk vs. reward of surgery as a disease 3 INADEQUATE PATIENT ACCESS Lack of guidelines, stakeholder misalignment, qualified surgeons, affordability and complex care pathway restricts access to therapy 10 4 SUBOPTIMAL OUTCOMES WITH VARIABILITY & Surgical. DURABILITY variability and insufficient patient post-intervention engagement negatively impacts outcomes & reputation

WOD events • Cairo University Hospital OPC • Ain Shams University Hospital OPC • Alexandria University OPC • Arab Bariatric Center OPC • Scientific Day at Ministry of Health Training Center with Media and newspapers Coverage • Private clinic Patients gathering events • Several activities on the most influencer bariatric surgeons social media channels. • Arabic version patient facing materials. • News paper publicity. 11

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THANK YOU 18