summary ovary produce ovum secret steroid hormones uterine








































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summary • ovary: produce ovum & secret steroid hormones. • uterine tube: transport ovum+fertilization • uterus: where embryonic & fetal development occurs. • vagina • external genitalia
一、ovary • capsule:epithulium + albuginea. • parenchyma:cortex + medulla • cortex:ovarian follicles + CT. • medulla:LCT + elastic f + blood vessels
ovary
(一)ovarian follicle • Follicle = an oocyte + surrounding follicul cells. • 4 steps : primordial、primary、 secondary and mature follicle 。
1. Primordial follicle • location: beneath the albuginea. • small & more. • primary oocyte + follicul C • primary oocyte : round , eosinophilic.
ovary
Primordial follicles
Primordial follicle
2. Primary follicle • primary oocyte. • Follicle C→proliferate, squamous→cuboidal or columnar, simple→stratified. • Zona pellucida: homogeneous.
Cortex of ovary
3. Secondary follicle • Primary oocyte: size increase to the apex. • antrum: follicular fluid, 6~ 12 layers of granulosa cells.
Secondary follicle
l Follicle C : granulosa C. l stratum granulosum :formed by several granulosa C , the wall. l Cumulus oophorus :primary oocyte + zona pellucida + corona radiata + granulosa C. protruding into the antrum
antrum Cumulus oophorus Granulosa cells
4. Mature follicle • secondary follicle→mature follicle • follicular fluid • the wall • move towards the surface of ovary. • primary oocyte →secondary oocyte
Mature follicle
Mature follicle
(二)ovulation • Mature follicle rupture,secondary oocyte + corona radiata + zona pellucida + follicular fluid, expelled from the follicle.
fate of secondary oocyte after ovulation • In 24 h, degenerate and disappear if not fertilizing. • Or else,go on with the 2 nd meiotic division,form haploid mature ovum.
(三)corpus luteum 1. Definition : after ovulation,the follicular wall, composed of the remaining granulosa & thecal cells , is thrown into deep folds as follicle collapse and is transformed into the corpus luteum. Show a yellow appearance in fresh preparations.
2. Functions of luteal cells • granular lutein C:progesterone & relaxin. • theca lutein C:estrogen
3. Classifications of corpus luteum • corpus luteum of menstruation : is formed in the absence of fertilization. • corpus luteum of pregnancy:is formed after fertilization and implantation.
二、uterine tube • infundibulum+ampulla+isthmus+uterine part • lumen is irregular • wall= mucosa+muscularis+serosa • mucosa= simple columnar Epi. +basal lamina • Epi. = secretory C + ciliated C • muscularis : inner circular, outer longitudinal SM
Uterine tube
Mucosa of uterine tube
Mucosa of uterine tube
三、uterus • body+fundus+cervix • wall=endometrium+myometrium +perimetrium
uterus
1. endometrium • Function layer: superficial, undergo cyclical changes. • Basal layer: deeper, proliferate & repair function layer. • • Epi=secretory C+ciliated C. Basal lamina=CT+stroma C+ uterine gland. • Uterine gland: Epi. Invaginate to form. • Coiled artery: the branch of uterine artery.
Cilia on the columnar C of endometrium
2. menstrual cycle • cyclical changes of Function layer • exfoliate、bleed、repair & proliferate • occur every 28 days, called…。 • menstrual phase: first 1~ 4 days • proliferative phase: 5 ~ 14 • secretory phase: 15 ~ 28
1. proliferative phase • • • Also called follicular phase。 Epithelial C+stroma C proliferate。 Early : uterine gland sparse、thin & short. • later: endometrium become thick, uterine gland increase ,coiled artery go up and convolute. • Ovulation in overy,endometrium transform into the secretory phase.
proliferative phase of endometrium
2. secretory phase • • • Also called luteum phase. Endometrium continue thickening. Uterine gland highly convolute,swell, filled by secretion. Stroma C hypertrophy. Coiled artery increase,more convoluted. If ovum is fertilized,endometrium keep thickening ,till into decidua,or else, into menstrual phase.
secretory phase of endometrium
3. menstrual phase • If fertilized occurred,coiled A contract, endometrium ischemic lead to necrosis of function layer. • Brief periods of blood flow,blood flow into function layer. disruption of the surface epithelial C & rupture of the blood. Wash out patches of tissue separated from endometrium discharge through vaginalis.