StructureFunction Interactions Kelly Riedell Brookings Biology SP 7

Structure/Function Interactions Kelly Riedell Brookings Biology SP 7: The student is able to connect and relate knowledge across various scales, concepts, and representations in and across domains

STRUCTURE Shape? , What it’s made of? How it is put together? FUNCTION What’s its job? How it acts? Properties? THIS IS NOT TELL ME FACTS ! ! Ligase Joins Okazaki fragments THIS IS NOT OBJECT/FUNCTION ! ! ! Mitochondria “Powerplant of cell”

STRUCTURE Shape? , What it’s made of? How it is put together? FUNCTION What’s its job? How it acts? Properties? AP LEVEL ANSWERS! ! Mitochondria X “Powerplant of cell” Burns glucose and stores energy released as ATP; Cellular respiration

STRUCTURE Shape? , What it’s made of? How it is put together? X Mitochondria FUNCTION What’s its job? How it acts? Properties? Burns glucose and stores energy released as ATP; Cellular respiration BE SPECIFIC WHAT IS IT ABOUT THE STRUCTURE THAT MAKES THE FUNCTION HAPPEN?

STRUCTURE Shape? , What it’s made of? How it is put together? Mitochondria have a double membrane which divides the interior into compartments FUNCTION What’s its job? How it acts? Properties? Allows separation of different biochemical pathways into different places inside mitochondria. Increased efficiency by localizing enzymes need in a pathway (Krebs cycle) together in same place (matrix) Creates a space for H+ ions to build up (intermembrane space) making a concentration gradient to power ATP production

STRUCTURE Shape? , What it’s made of? How it is put together? Folding in cristae membrane Phospholipid tails in membranes are hydrophobic Charge on H+ ions FUNCTION What’s its job? How it acts? Properties? Increases surface area for greater transport of H+ ions across membrane by ETC proteins Allows formation of H+ gradient; Keeps charged H+ ions from leaking out of intermembrane space without passing through ATP synthase Prevents passage of ions across membranes without going through a transport protein: actively pumped into intermembrane space by ETC proteins; return to matrix passively through ATP synthase to make ATP

STRUCTURE Shape? , What it’s made of? How it is put together? A-T has 2 hydrogen bonds G-C has 3 hydrogen bonds FUNCTION What’s its job? How it acts? Properties? Easier to separate /open DNA strand in areas with lots of A-T ‘s (TATA boxes). RNA polymerase can start reading code easier here awdfasdfasdfasdf sdfasdff asdfasdf

STRUCTURE Shape? , What it’s made of? How it is put together? DNA can exist in a less tightly packed CHROMATIN form DNA can exist in a more tightly packed CHROMOSOME form During replication, nucleotide subunits come in as tri-phosphates FUNCTION What’s its job? How it acts? Properties? Allows access to DNA code for replication and transcription Makes it easier for cells to move during mitosis/meiosis Bring their own build in energy to join strand ADD EXAMPLES TO YOUR BILL You DON’T need to add them ALL Pick the best examples or make up your own Make sure they give specific descriptions about the structure & details about how the structure affects its properties! Add pictures if you like to illustrate your examples

STRUCTURE Shape? , What it’s made of? How it is put together? awewd FUNCTION What’s its job? How it acts? Properties? asdlfkh asdflhk assdf awdfasdfasdfasdf sdfasdff asdfasdf