Structural Classification of the Nervous System 1 Central

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Structural Classification of the Nervous System § 1. Central nervous system (CNS) § §

Structural Classification of the Nervous System § 1. Central nervous system (CNS) § § § 2. Peripheral nervous system (PNS) § § Cranial and spinal nerves 1 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Functions of the Nervous System 1. Sensory input – (PNS) § 2. Integration (CNS)

Functions of the Nervous System 1. Sensory input – (PNS) § 2. Integration (CNS) § 3. Motor output (PNS) § 2 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Functions of Peripheral Nervous System (3 slides) § Sensory (afferent) division § 3 Figure

Functions of Peripheral Nervous System (3 slides) § Sensory (afferent) division § 3 Figure 7. 1 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Functions of Peripheral Nervous System § Motor (efferent) division § Two subdivisions - Somatic

Functions of Peripheral Nervous System § Motor (efferent) division § Two subdivisions - Somatic nervous system - Autonomic nervous system- 2 subdivisions § Sympathetic § Parasympathetic Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings 4 Figure 7. 1

Organization of the Nervous System 5 Figure 7. 2 Copyright © 2006 Pearson Education,

Organization of the Nervous System 5 Figure 7. 2 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Compare/Contrast Motor Divisions SOMATIC NS AUTONOMIC NS § 2 branches – sympathetic and parasympathetic

Compare/Contrast Motor Divisions SOMATIC NS AUTONOMIC NS § 2 branches – sympathetic and parasympathetic § Uses acetylcholine, epinephrine, norepinephrine § 6 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Comparison of Somatic and Autonomic Nervous Systems 7 Figure 7. 24 Copyright © 2006

Comparison of Somatic and Autonomic Nervous Systems 7 Figure 7. 24 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Autonomic NS Branches § Parasympathetic- § Remember as the “D” division - digestion, defecation,

Autonomic NS Branches § Parasympathetic- § Remember as the “D” division - digestion, defecation, and diuresis § Sympathetic – § Remember as the “E” division = extreme exercise, excitement, emergency, and embarrassment ** Both systems work in conjunction with one another to maintain homeostasis** Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings 8

9 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

9 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Types of Supporting Cells § Neuroglia – Nerve Glue (supporting cells) § AKA –

Types of Supporting Cells § Neuroglia – Nerve Glue (supporting cells) § AKA – glial cells § § Types § Astrocytes § Microglia § Ependymal § Oligodendrocytes § Schwann cells and Satellite Cells (PNS) Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings 10

CNS: Support Cells § Astrocytes § Microglia § Spider-like phagocytes Figure 11 7. 3

CNS: Support Cells § Astrocytes § Microglia § Spider-like phagocytes Figure 11 7. 3 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

CNS: Support Cells § Ependymal cells § Oligodendrocytes § Produce myelin sheath around nerve

CNS: Support Cells § Ependymal cells § Oligodendrocytes § Produce myelin sheath around nerve fibers Figure 12 7. 3 b–c Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

PNS: Support Cells (2 major types) § 1. Satellite cells § § 2. Schwann

PNS: Support Cells (2 major types) § 1. Satellite cells § § 2. Schwann cells § Figure 13 7. 3 e Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Nervous Tissue: Neurons § Neurons = nerve cells § Major parts of a neuron

Nervous Tissue: Neurons § Neurons = nerve cells § Major parts of a neuron § Cell body – § Processes – 14 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Neuron Anatomy § Cell body § Nissl substance § Neurofibrils – Figure 15 7.

Neuron Anatomy § Cell body § Nissl substance § Neurofibrils – Figure 15 7. 4 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Neuron Anatomy § Processes § Dendrites – § Axons – Figure 16 7. 4

Neuron Anatomy § Processes § Dendrites – § Axons – Figure 16 7. 4 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Axons and Nerve Impulses Axons (cont’d) § Synaptic cleft § Synapse 17 Copyright ©

Axons and Nerve Impulses Axons (cont’d) § Synaptic cleft § Synapse 17 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Nerve Fiber Coverings § Schwann cells – ? § Nodes of Ranvier – §

Nerve Fiber Coverings § Schwann cells – ? § Nodes of Ranvier – § Oligodendrocytes - ? Figure 18 7. 5 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

§ Label a neuron 19 Copyright © 2006 Pearson Education, Inc. , publishing as

§ Label a neuron 19 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Vocab: CNS § CNS – contains mostly cell bodies § Gray matter – §

Vocab: CNS § CNS – contains mostly cell bodies § Gray matter – § Tracts § White matter – 20 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Functional Classification of Neurons (3) § 1. Sensory (afferent) neurons (PNS) § Special Sense

Functional Classification of Neurons (3) § 1. Sensory (afferent) neurons (PNS) § Special Sense § Cutaneous sense organs § Proprioceptors – § 2. Association neurons (interneurons) § CNS § 3. Motor (efferent) neurons § 21 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Neuron Classification Figure 22 7. 6 Copyright © 2006 Pearson Education, Inc. , publishing

Neuron Classification Figure 22 7. 6 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

§ Video : Review “Creation of a Nerve Impulse” § Video: Review “Nerve impulse

§ Video : Review “Creation of a Nerve Impulse” § Video: Review “Nerve impulse propagation” 23 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

§ B NOTES 24 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin

§ B NOTES 24 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

4 Main Regions of the Brain § 1. Cerebral hemispheres § 2. Diencephalon §

4 Main Regions of the Brain § 1. Cerebral hemispheres § 2. Diencephalon § 3. Brain stem § 4. Cerebellum § Brain song Figure 25 7. 12 b Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Cerebral Hemispheres (Cerebrum) Cerebrum § § § Gyri (pl) – § Sulci (pl) –

Cerebral Hemispheres (Cerebrum) Cerebrum § § § Gyri (pl) – § Sulci (pl) – § Fissures – § Figure 26 7. 13 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Lobes of the Cerebrum § Lobes of the cerebrum § Frontal lobe Insula §

Lobes of the Cerebrum § Lobes of the cerebrum § Frontal lobe Insula § Parietal lobe § Occipital lobe § Temporal lobe § Insula 27 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Layers of the Cerebrum 3 slides § Cerebral cortex (Gray matter) § § §

Layers of the Cerebrum 3 slides § Cerebral cortex (Gray matter) § § § Figure 7. 13 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Specialized Areas of the Cerebrum Speech, memory, consciousness, emotional and logical response, voluntary movement,

Specialized Areas of the Cerebrum Speech, memory, consciousness, emotional and logical response, voluntary movement, interpretation of sensation Figure 7. 13 c Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

§ Cerebral Cortices Notes 30 Copyright © 2006 Pearson Education, Inc. , publishing as

§ Cerebral Cortices Notes 30 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Lobotomy 31 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Lobotomy 31 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Layers of the Cerebrum games § Cerebral White matter § § § Ex: corpus

Layers of the Cerebrum games § Cerebral White matter § § § Ex: corpus callosum connects hemispheres Figure 32 7. 13 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Layers of the Cerebrum § Basal nuclei (basal ganglia) – internal islands of gray

Layers of the Cerebrum § Basal nuclei (basal ganglia) – internal islands of gray matter § § Figure 33 7. 13 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Diencephalon – “interbrain” Diencephalon § § § Made of three parts § Thalamus §

Diencephalon – “interbrain” Diencephalon § § § Made of three parts § Thalamus § Hypothalamus § Epithalamus 34 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Diencephalon: Thalamus 35 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Diencephalon: Thalamus 35 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Diencephalon: Hypothalamus § Important autonomic n. s. center § part of the limbic system

Diencephalon: Hypothalamus § Important autonomic n. s. center § part of the limbic system § Mammillary bodies (smell) hang off of hypothalamus 36 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Diencephalon: Epithalamus § Houses the pineal body (an endocrine glandsleep/wake cycles) 37 Copyright ©

Diencephalon: Epithalamus § Houses the pineal body (an endocrine glandsleep/wake cycles) 37 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Review location/function on diencephalon Figure 38 7. 15 a Copyright © 2006 Pearson Education,

Review location/function on diencephalon Figure 38 7. 15 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Brain Stem Parts of the brain stem § Midbrain § Pons § Medulla oblongata

Brain Stem Parts of the brain stem § Midbrain § Pons § Medulla oblongata 39 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Midbrain § Mostly tracts of nerve fibers § Cerebral peduncles§ ascend and descend impulses

Midbrain § Mostly tracts of nerve fibers § Cerebral peduncles§ ascend and descend impulses § Corpora quadrigemina - 40 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Pons (“bridge”) § Below midbrain 41 Copyright © 2006 Pearson Education, Inc. , publishing

Pons (“bridge”) § Below midbrain 41 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Medulla Oblongata Contains vital visceral? control centers 42 Copyright © 2006 Pearson Education, Inc.

Medulla Oblongata Contains vital visceral? control centers 42 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Review location/functions of 3 parts of brainstem 43 Copyright © 2006 Pearson Education, Inc.

Review location/functions of 3 parts of brainstem 43 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

§ Reticular formation – gray matter running length of brain stem § RAV –

§ Reticular formation – gray matter running length of brain stem § RAV – reticular activating system 44 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Cerebellum § balance and equilibrium 45 Copyright © 2006 Pearson Education, Inc. , publishing

Cerebellum § balance and equilibrium 45 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Protection of the Central Nervous System Figure 46 7. 16 a Copyright © 2006

Protection of the Central Nervous System Figure 46 7. 16 a Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Meninges – 3 layers § Dura mater – “tough or hard mother” § §

Meninges – 3 layers § Dura mater – “tough or hard mother” § § Periosteum – § Meningeal layer – § Arachnoid layer § § Arachnoid villi – § Pia mater (deepest) § § 47 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Cerebrospinal Fluid (CSF) § Similar to blood plasma § Formed by the choroid plexus?

Cerebrospinal Fluid (CSF) § Similar to blood plasma § Formed by the choroid plexus? (epithalamus) § Hydrocephalus – § Corrected by shunts 48 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

49 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

49 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Blood Brain Barrier § Composed of the least permeable capillaries of the body §

Blood Brain Barrier § Composed of the least permeable capillaries of the body § Useless against some substances § Glucose and water § Fats and fat soluble molecules § Respiratory gases § Alcohol § Nicotine § Anesthesia Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings 50

Traumatic Brain Injuries § Concussion § § § Contusion § Nervous tissue destruction occurs

Traumatic Brain Injuries § Concussion § § § Contusion § Nervous tissue destruction occurs § (stem cells? ) § Cerebral edema § § 51 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Cerebrovascular Accident (CVA) § Stroke – 3 rd leading cause of death § TIA

Cerebrovascular Accident (CVA) § Stroke – 3 rd leading cause of death § TIA (transient ischemic attack) – “mini stroke” § 80% of strokes are preventable 52 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Alzheimer’s Disease § Structural changes in the brain § include abnormal protein deposits (beta

Alzheimer’s Disease § Structural changes in the brain § include abnormal protein deposits (beta amyloid) § shortage of Ach § twisted fibers within neurons (due to Tau (protein) malfunction) § Symptoms: 53 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

54 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

54 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings

Development Aspects of the Nervous System § Fetal Development § Child/Young Adult Development §

Development Aspects of the Nervous System § Fetal Development § Child/Young Adult Development § Old Adult 55 Copyright © 2006 Pearson Education, Inc. , publishing as Benjamin Cummings