Sterile BlowFillSeal by UNITHER BlowFillSeal Features Specifications Single

Sterile Blow-Fill-Seal by UNITHER

Blow-Fill-Seal | Features Specifications Single dose unit Sterile From 0, 25 ml to 20 ml Benefits Preservative free (Sterile) Dosage accuracy Easy to carry Therapeutic Areas Ophthalmology Rhinology Asthma Antisepsis Wound cleaning

Blow-Fill-Seal | Capabilities First BFS Manufacturer Worldwide Current capacity of 2, 5 Billion SDU / year 4 Manufacturing plants Dual sourcing supply securization Industrial capacities 24 Rotative Bottle-pack lines 4 Alternative Bottle-pack lines Moulds from 0, 25 ml to 20 ml Development & Analytics BFS dedicated development team Large expertise Pilot workshop

Blow-Fill-Seal | Global organization 4 Manufacturing sites - BFS • Amiens – France • Gannat - France • Coutances – France • Rochester – USA Rochester, NY USA Manufacturing sites

Blow-Fill-Seal | Process Blow Fill Seal in one operation and one machine ❶ Extrusion of PE ❷ Blowing ❸ Filling ❹ Sealing ❺ Unmoulding

Blow-Fill-Seal | Rotative filling of the solution Steam sterilisation of the BP Sterilizing filtration of the air in contact with the solution Compressed air Sterilizing filtration of the air to blow the balloon Buffer tank Solution 1 st sterilizing filtration Dosage valves 2 nd sterilizing filtration Granules of PE Extrusion PE Balloon

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