Starter recessive Cystic fibrosis is a disorder This

Starter recessive Cystic fibrosis is a ………………. . disorder. This means that in order to develop the condition you two cystic fibrosis…………, alleles one need to inherit……… mother from your ……………and one from your father. If you inherit only one cystic fibrosis allele, you are carrier symptoms called a ………………. . and do not have……………. . . symptoms alleles mother carrier recessive two © Snapshot Science, 2010

Activity Imagine: You have a brother who has cystic fibrosis. Your parents do not have the illness. What is the probability that you are a carrier? Draw out the genetic cross to show you figured this out. Mum c C CC Cc cc Dad C 25% chance of not being affected. 50% chance of being a carrier. 25% chance of having cystic fibrosis.

Activity Jeans for Genes is a charity that raises money to go to organisations that research cures into genetic diseases like cystic fibrosis. It is Jeans for Genes day and you have been asked to talk about cystic fibrosis in a school assembly. Your presentation needs to include: • • The symptoms of CF How the illness affects your brother’s life How the illness is treated How gene therapy may cure the illness in the future

Assessment I am working at grade. . I can. . E Remember and use Write down key the facts symptoms of cystic them to answer simple questions fibrosis C Apply what know symptoms to new Explain why. I these occur. situations. Use science explain Describe a treatment forto. CF. things. A Explain what gene therapy is and Understand explain more how it couldand be used in the future complex scientific ideas. Link to cure CF. ideas together to explain the ‘bigger picture’