STAAR Visian ICL Stateoftheart Vision Correction June 2015

STAAR Visian ICL State-of-the-art Vision Correction June, 2015 Kyiv 1

S. T. A. A. R. Surgical üTechnology üAnd üAdvanced üResearch

STAAR Surgical worldwide ICL MFG Intl HQ Switzerland HQ USA Fastest growing markets: Asia

The ICL - History • • • 1991 First implantations (Fyodorov, Russia) 1993 First modern STAAR ICL implanted (Pesando, Italy) V 1 -V 3 1997 CE marking and official launch 1998 Latest design V 4 2002 CE Marking Toric 2005 US FDA Approval 2010 Approval in Japan 2011 CE marking V 4 C 2013 >400 k lenses implanted worldwide ! 2014 CE marking China

Proven Safety Record ü >500 k lenses implanted globally ü >100 k Visian Toric ICLs implanted globally ü Visian ICL V 4 C approved in every major refractive market (EU, China, Korea, Japan, Brazil, India) ü The Visian ICL has a track record of stable, consistently excellent clinical outcomes. ü Currently sold in more than 90 countries

Visian ICL Details ® § Posterior Chamber location ü ü Safe distance from the endothelium Cosmetically invisible for patient Gain in retinal image size, increased magnification for patient Greater effective Optical Zone at the corneal plane § Sulcus Location ü ü Stable location allowing for Toric design Easily removable /exchangable No fixation to surrounding tissues Does not alter shape/remove tissue maintaining treatment flexibility for the future ü Does not induce dry eye.

What is the ICL ? • The ICL can correct: – Nearsightedness (Myopia) – Farsightedness (Hyperopia) – Astigmatism §One of the widest treatment ranges of any refractive product: From -0. 5 D to -18. 0 D Spherical correction From +0. 5 D to +10. 0 D Spherical Correction From 0. 5 D to 6. 0 D of Astigmatism correction

Visian ICL Product Details ® § Made of Collamer®: Collagen and HEMA copolymer ü Excellent biocompatibility resulting in quiet eyes ü Excellent transmittance and low reflectance patterns (no haloes or glare) ü UV chromophore which may help protect the retina from UV rays ü Very flexible (foldable, small incision, easy to inject, remove)

Why COLLAMER? • Soft and foldable and inserted through micro-incision Quicker visual recovery • Because of the biocompatibility, the ICL is not recognized as a foreign body Happy Eyes after surgery • Collamer contains a UV filter which protects against the negative effect of the sun on the crystalline lens and the retina. Protection of crystalline lens and retina

ICL is Very Thin < 100 um < 50 microns 500 -600 um

Visian ICL with Centra. FLOW ü Made of proprietary biocompatible Collamer material ü Central Optic port of 360µ, eliminates the need for PI’s ü Also has Extended alignment markings on the Toric model >100. 000 implants

Advantages of ICL ü The central cornea remains entirely untouched ü Dry eyes complications do not occur ü Super Optical clarity of a lens-based additive surgery, rather than a tissue procedure ü My patient will have a “HD Vision” outcome without as much of the glare and halos often seen with LVC

Advantages of ICL ü Should my patient not like their vision, the ICL can be removed ü Subsequent IOL calculations for cataract surgery (when the patient is older) will not be affected since there has been no corneal refractive procedure ü Visual recovery is rapid

Growing indications • Moderate to high myopia • Patients with high expectations (HDVision, need for better night vision) • Patients with thin corneas • Patients with irregular corneas (Stable KC) • Patients with large pupils

Contraindications • • • Glaucoma Cataract, early or advanced ACD less than 2. 8 mm Age over 45 Non-stable KC

Benefits of ICL • Wide range of correction (safe and effective also for very high degrees!) • Superior quality of vision • Better predictability (no healing!) and stability (no regression!) • Better night vision • Faster recovery • No tissue is permanently removed from the cornea • Removable (reversibility of the surgery) • Eye remains unchanged for future procedures!

Thank you!! 4 Company Confidential