Skin and appendages Mammary gland Dr Szuk Andrs

Skin and appendages. Mammary gland Dr. Szuák András EM 2018. 11. 1.

Skin • Epidermis • Dermis • Hypodermis

Thick skin Thin skin

Epidermis 5 • stratified keratinized squamous epithelium • • • 3 str. basale/germinativum (1) str. spinosum/poligonale (2) str. granulosum (3) str. lucidum (4) str. corneum (5) 2 1 4

Cells of epidermis • Keratinocyte (keratinizing, wound healing) • Melanocyte (cytocrine secretion of pigments) • eumelanin, pheomelanin • Langerhans cell (antigen-presenting, Birbeck-gr. ) • Merkel cell

Dermis papillary layer reticular layer

Receptors in the skin • free nerve endings • Merkel cell (epidermis) • Meissner corpuscle • Pacinian corpuscle • Ruffini corpuscle • Krause corpuscle (cold, Bulbous corp. )

Skin relief • ridges and furrows on the surface of the skin • arch • whorl • loop

Glands

Hair follicle • Growth cycle • anagen phase (growth) • catagen phase (getting shorter) • telogen phase (abscence of bulb)

Hair follicle sebaceous gl. arrector pili m. Cuticle

Hair follicle External root sheath cortex Cuticle Internal root sheath papilla early cultilce cells connective tissue Internal root sheath processes of melanocytes Matrix

INFUNDIBULUM ISTHMUS, MIDDLE ISTHMUS, LOWER PART external root sh. hair r hai external root sh. stratum corneum stratum granulosum internal root sheath (Huxley’s layer) cuticles internal root sheath (Henle’s layer)

cuticles

lateral nail groove and lateral fold Nail proximal fold eponychium lunula hyponychium

Nail bed dorsal matrix ventral matrix proximal fold eponychium

Blood supply subpapillary plexus Arteriovenous shunt cutaneous plexus

Mammary gland areola mammary papilla

Non-lactating Lactatnig

Mammary gland

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