Severe Combined Immunodeficiency SCID Severe Combined Immunodeficiency SCID

Severe Combined Immunodeficiency (SCID)

Severe Combined Immunodeficiency (SCID)

What is SCID? • Severe Combined Immunodeficiency, otherwise known as SCID. • SCID is a group of very rare-and potentially fatal-inherited disorders related to the immune system. • SCID makes those affected highly susceptible to life-threatening infections by viruses, bacteria and fungi.

What is SCID? • Severe Combined Immunodeficiency, otherwise known as SCID. • SCID is a group of very rare-and potentially fatal-inherited disorders related to the immune system. • SCID makes those affected highly susceptible to life-threatening infections by viruses, bacteria and fungi.

Is SCID Inherited?

Is SCID Inherited?

Chromosome Location? • There are several types of SCID. • The most common form is caused by a mutation in the SCIDX 1 gene located on the X chromosome.

Chromosome Location? • There are several types of SCID. • The most common form is caused by a mutation in the SCIDX 1 gene located on the X chromosome.

Interesting Facts! • One form of SCID became the first human illness treated by human gene therapy in 1990. • About 1 out of every 100, 000 babies is born with SCID. • SCID is sometimes called Bubble Boy disease. In the 1970 s, a boy named David Vetter had to live in a plastic bubble for 12 years because of SCID.

Interesting Facts! • One form of SCID became the first human illness treated by human gene therapy in 1990. • About 1 out of every 100, 000 babies is born with SCID. • SCID is sometimes called Bubble Boy disease. In the 1970 s, a boy named David Vetter had to live in a plastic bubble for 12 years because of SCID.

Citations • http: //www. genome. gov/13014325 • http: //learn. genetics. utah. edu/content/disorders/w hataregd/scid/ IMAGES • http: //kidshealth. org/Page. Manager. jsp? dn=girlshea lth&lic=175&cat_id=132&article_set=21836 • US national library of Health