Serum Hepcidin Levels Iron Dyshomeostasis and Cognitive Loss

Serum Hepcidin Levels, Iron Dyshomeostasis and Cognitive Loss in Alzheimer&#x 02019; s Disease Sternberg Zohara, Hu Zihua, Sternberg Daniel, Waseh Shayan, Quinn Joseph F. , Wild Katharine, Jeffrey Kaye, Zhao Lin, Garrick Michael 1 Department of Neurology, Stroke Center, Buffalo Medical Center, Buffalo, NY, USA. 2 Center for Computational Research, New York State Center for Excellence in Bioinformatics and Life Sciences, University at Buffalo, NY, USA. 3 Department of Biology, State University of New York at Buffalo, NY 14260 USA. 4 Layton Aging &#x 00026; Alzheimer&#x 00027; s Research Center, Oregon Health and Science University, Portland, Oregon, USA. 5 Department of Biochemistry, State University of New York at Buffalo, NY 14214 USA. 6 Department of Pediatrics, State University of New York at Buffalo, NY 14214 USA. Figure 3. Correlations between measurements depend on diagnosis. For each panel, lines of regression indicate the existence or absence of a correlation and the shaded region shows the 95&#x 00025; confidence interval (CI) with data stratified by diagnosis of AD or control for hepcidin versus iron (A), hepcidin versus TIBC (B), hepcidin versus ferritin (C), and A&#x 003 B 2; 40 versus A&#x 003 B 2; 42 (D). Aging and Disease, 2017, 8(2), 215 -227. DOI: 10. 14336/AD. 2016. 0811