Sedatives Sedatives Uses z Uses y Preanesthetic y

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Sedatives

Sedatives

Sedatives- Uses z Uses: y. Preanesthetic y. Antiepileptic y. Anxiolytic y. Treat insomnia y.

Sedatives- Uses z Uses: y. Preanesthetic y. Antiepileptic y. Anxiolytic y. Treat insomnia y. Muscle relaxation

Sedatives - Actions z Action: y. Enhances GABA y. Effects on acetylcholine and dopamine

Sedatives - Actions z Action: y. Enhances GABA y. Effects on acetylcholine and dopamine y. Calming effects y. Decrease anxiety z Side effects y. Drowsiness, confusion y. Depress respiratory system y. Synergistic effects w/alcohol y. GI problems y. Dependence

Sedatives - Categories z Barbituates - Schedule II, III & IV ygreat risk of

Sedatives - Categories z Barbituates - Schedule II, III & IV ygreat risk of O. D. - toxic amount 10 times recommended dose y(Phenobarbital) y(Pentobarbital)

Sedatives - Categories z Benzodiazepines - Schedule IV yless risk of O. D. y.

Sedatives - Categories z Benzodiazepines - Schedule IV yless risk of O. D. y. Valium (Diazepam) xanxiety, muscle relaxation x. Side effects - drowsiness, fatigue, ataxia y. Xanax (Alprazolam) xpanic attacks, anxiety xless “buzz” effect than Valium

Benzodiazepines - Hypnotics y. Halcion (Triazolam) xtreat insomnia xside effects - “hangover feeling”, headache,

Benzodiazepines - Hypnotics y. Halcion (Triazolam) xtreat insomnia xside effects - “hangover feeling”, headache, nausea, blurred vision, memory loss xwas taken off the market for a while y. Restoril (Temazepam) x“hangover feeling” y. Dalmane (Flurazepam)

Treatment of sleeplessness z Legitimate uses of sleeping meds. z Other ways to treat

Treatment of sleeplessness z Legitimate uses of sleeping meds. z Other ways to treat insomnia z OTC sleeping meds. - take >20 min. to work y. Diphenhydramine y. Side effect - drowsiness

Sedatives z Very addicting z Very dangerous to quit “cold turkey” z Withdrawal Symptoms

Sedatives z Very addicting z Very dangerous to quit “cold turkey” z Withdrawal Symptoms y. Physical xtremors, shakes, headache, insomnia, convulsions y. Psychological xirritability, anxiety, restlessness

Rohypnol z Powerful sleep inducing drug z Schedule I drug – Controlled Substances Act

Rohypnol z Powerful sleep inducing drug z Schedule I drug – Controlled Substances Act z Banned Benzodiazepine z Made in the U. S. – legal in Mexico

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