SCIENTIFIC COORDINATORS ORGANISING COMMITTEE Scientific Coordinators Prof Michael

SCIENTIFIC COORDINATORS ORGANISING COMMITTEE Scientific Coordinators Prof. Michael Przybilski, Ph. D Department of Chemistry, University of Konstanz, Germany Scientific Program Committee Prof. Konrad Sandhoff, Ph. D Prof. Eser Yıldırım Sözmen, MD, Ph. D Department of Medical Biochemistry, Ege University, School of Medicine, Türkiye President of The Turkish Biochemical Society, Türkiye Kekulé-Institut f. Organische Chemie und Biochemie Rheinische Friedrich-Wilhelms-Universitaet Bonn, Germany Prof. Nazmi Özer, Ph. D Prof. Asuman Özkara, MD Department of Medical Biochemistry, Hacettepe University School of Medicine, Türkiye Asc. Prof. Sema Kalkan Uçar, MD CONFERENCE CONTACT ADRESSES Department of Metabolic Disease Children Hospital, Ege University School of Medicine, Türkiye FEBS ADVANCED LECTURE COURSE 360 O LYSOSOME; FROM STRUCTURE TO GENOMICS, FROM FUNCTION TO DISEASE 23 -28 OCTOBER 2014 IZMIR, TURKIYE Prof. Mahmut Çoker, MD Course Information e-mail: info@febs-lysosome. org Department of Metabolic Disease Children Hospital, Ege University School of Medicine, Türkiye Registration e-mail: 360 lysosome 2014@gmail. com Department of Developmental and Molecular Biology Institute for Aging Research, Albert Einstein College of Medicine, USA Grant Application e-mail: grants@febs-lysosome. org Prof. Ana Maria Cuervo, MD Asc. Prof. Devrim Gözüaçık, MD, Ph. D Faculty of Engineering and Natural Sciences, Sabancı University, Turkiye General Inquiries Department of Medical Biochemistry, Ege University School of Medicine, Bornova, Izmir, 35100 Turkiye Phone: +90 232 390 4031, Fax: +90 232 390 4030 IMPORTANT DATES Date Important Dates & Deadlines June 30 th, 2014 Deadline for grant application and abstract submission July 25 th, 2014 Deadline for registration July 30 th, 2014 August 15 th, 2014 Letters of acceptance to all participants and notification about presentation Deadline for payment of registration fee Local Organizing Committee Asc. Prof. Ebru Sezer, MD Prof. Ferhan G. Sağın, MD, Ph. D Prof. Hikmet Hakan Aydın, MD Prof. Nevbahar Turgan, MD Prof. Yasemin Akçay, MD Department of Medical Biochemistry, Ege University, School of Medicine, İzmir Turkiye Pine Bay Hotel Camlimani Mevkii, 09400 Kuşadası / Aydın / Turkiye http: //www. febs-lysosome. org

WELCOME This course is designed for all researchers working on lysosomes – i. e. cell biologists, biochemists, geneticists, laboratory professionals, and health care professionals who deal with lysosomal storage disorders (LSD’s). During the course, the molecular and cellular aspects of LSDs as well as the role of lysosomes in normal metabolism and pathological processes in all living cells will be discussed in a dynamic format of plenaries, panels, poster and oral discussion sessions REGISTRATION The registration will be open to applicants from January 2 nd, 2014 and will close on July 25 th, 2014. The registration fee includes full board, lodging (in a double-room share basis)* and program material. 370 € (students, person in a double room)** 550 € (senior/corporate scientists) * for single rooms an additional payment of 175 € (35 € per night) is required. ** students include both: Ph. D students and postdocs. A proof of this status must accompany payment. Accompanying person(s); 300 € (per person in a double room-all-inclusive, 5 nights). PAYMENT Payment must be kindly made exclusively by bank transfer (net of all bank charges) to the following account, between January 2 nd and September 1 st, 2014. GARANTI BANK/ KORDON BRANCH TL Account IBAN: TR 18 0006 2000 8650 0006 2985 50 EURO Account IBAN: TR 67 0006 2000 8650 0009 0939 84 In the bank transfer description please indicate your name and FEBS Course 2014. PROGRAMME Keynote Opening Lecture- EMBO Lecture Overview on the development of lysosomal research, K. Sandhoff IUBMB Lecture Lysosomes: fusion and function, P. Luzio Plenary Lectures Lysosomal biogenesis and homeostasis, R. Puertollano Selective autophagy and metabolism-A. M. Cuervo Regulation of autophagy in health and disease, D. Gözüaçık Protein degradation by autophagy, J. Dengjel Lysosomes as targets for cancer therapy –M. Jäättelä Pathological mechanisms in neuronal forms of Gaucher disease, A. Futerman Understanding the biological role of sialidases in glycolipid metabolism using mouse models, V. Seyrantepe Lysosomal proteomics and disease, P. Lobel Sphingolipidoses and the lipid phase problem, K. Sandhoff Glycosphingolipid storage diseases in Turkiye: from disease to the basic molecular mechanisms, A. Özkara Panels Panel 1 - Diagnostic methods of LSD’s Dried blood specimens in the diagnosis of lysosomal diseases, Z. Lukacs Mass spectrometric diagnostics of lysosomal diseases - new methods and clinical applications, M. Przybylsiki Diagnosis of LSD’s: combining input from different disciplines, S. Sansen Enzymatic diagnosis of LSD; effectiveness and reliability, E. Sözmen Panel 2 - Clinical Management of LSD’s Treatment modalities of LSD’s, M. Scarpa Discussion on Clinical vignettes - M. Çoker and S. Uçar PROGRAMME (Continued) Special Sessions Breakfast & Meeting time for Young Scientists Professional Development is a preferential slot which will deal with hot issues in the postgraduate education and further academic and/or industrial careers of young scientists. This informal slot will include 1 hour on 3 consecutive mornings of the course during which selected participants will get equipped with various issues like finding grants & jobs, writing CV’s, handling interviews, pursuing good academic and professional networking, etc. while having their breakfast, F. Sağın Round Table Discussion (selected special topics) Discussion on a special topic with experts in a small group. Each session will be 45 minutes. Maximum 2 topics will be selected. Selected Oral Communications 10 min. presentation+5 min. discussion Short Talk-Poster sessions Poster bullets (3 min presentation + 2 min discussion) TUBITAK SUPPORT PROGRAMME TUBITAK (The Scientific and Technological Research Council of Turkey) 2217 Graduate Summer School and Other Activities Supporting Program application will be made for travel and accommodation expenses of young researches who attend to the event. In the case of support, grant applications will be evaluated by the Organizing Committee. http: //www. febs-lysosome. org