Salivary Gland Parotid Gland Submandibular gland Sublingual gland

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Salivary Gland

Salivary Gland

 Parotid Gland. Submandibular gland. Sublingual gland. Minor salivary glands in floor of mouth,

Parotid Gland. Submandibular gland. Sublingual gland. Minor salivary glands in floor of mouth, pharynx, tongue & cheeks

Secretory unit : Acinus • • Acinar cells Intercalated duct cells. Striated Duct cells.

Secretory unit : Acinus • • Acinar cells Intercalated duct cells. Striated Duct cells. Secretory Duct cells. • • Mechanism of secretion of Saliva Active secretion Primary secretion Modification of primary secretion

Parotid gland: Entirely serous gland. Largest salivary gland. Rich in water and electrolyte and

Parotid gland: Entirely serous gland. Largest salivary gland. Rich in water and electrolyte and lack mucin. 25% of total salivary secretion. Duct of Stensen - level of 2 nd molar teeth

Sublingual Gland: Predominantly gland. Sublingual mucous duct(Ducts of Rivinus) Mucous : serous = 4:

Sublingual Gland: Predominantly gland. Sublingual mucous duct(Ducts of Rivinus) Mucous : serous = 4: 1 5% of total salivary secretion

Submandibular Gland : Mixed type. Ducts of Wharton (Submandibular ducts). 70% of total salivary

Submandibular Gland : Mixed type. Ducts of Wharton (Submandibular ducts). 70% of total salivary secretion

 Serous cells : Digestive enzymes. Mucous cells: Mucin. Intercalated and striated cells: Modifies

Serous cells : Digestive enzymes. Mucous cells: Mucin. Intercalated and striated cells: Modifies the ionic composition of the saliva.

Blood flow: Blood flow and metabolism secretion. 10 times α rate of saliva than

Blood flow: Blood flow and metabolism secretion. 10 times α rate of saliva than the active skeletal muscle. Parasympathetic stimulation- increase in salivary secretion.

Nerve supply

Nerve supply

 1. EFFERENT NERVE SUPPLY: - Parasympathetic nerve supply - Sympathetic nerve supply 2.

1. EFFERENT NERVE SUPPLY: - Parasympathetic nerve supply - Sympathetic nerve supply 2. AFFERENT NERVE SUPPLY: - VII & IX cranial nerves •

Saliva First digestive juice to come in contact with food Composition of saliva: Rate

Saliva First digestive juice to come in contact with food Composition of saliva: Rate of secretion : 1 ml / min; Daily secretion: 1 -1. 5 L / day. Max during meals and minimum during sleep. p. H = < 7 Color= colorless.

Saliva Solid(0. 5%) Water(99. 5%) Inorganic (0. 2%) Organic (0. 3%) Na+ , Cations

Saliva Solid(0. 5%) Water(99. 5%) Inorganic (0. 2%) Organic (0. 3%) Na+ , Cations K+ , Ca 2+ , Mg 2+ Anions Cl- , Hco 3 - , Po 4 -

Organic substances : Enzymes: Ptyalin/Salivary amylase Lingual lipase, Kallikreins Mucin Lysozymes Nerve growth factors

Organic substances : Enzymes: Ptyalin/Salivary amylase Lingual lipase, Kallikreins Mucin Lysozymes Nerve growth factors Immunoglobulins Proteins

Regulation of salivary secretion: Exclusively regulated by Neural mechanism 1. Spontaneous secretion 2. Reflex

Regulation of salivary secretion: Exclusively regulated by Neural mechanism 1. Spontaneous secretion 2. Reflex secretion

Spontaneous secretion In the absence of any known stimulation. Exp: Atropine and Cyanide. Depends

Spontaneous secretion In the absence of any known stimulation. Exp: Atropine and Cyanide. Depends on the metabolic activity of the gland. v Keeps the oral cavity moist.

Reflex secretion Unconditioned reflex : Stimulus: Presence of food in the oral cavity Previous

Reflex secretion Unconditioned reflex : Stimulus: Presence of food in the oral cavity Previous experience not necessary Conditioned reflex Stimulus: Sight, Smell, Thought Based on previous experience

Functions of saliva: ü Preparation lubrication. ü Solventü Help of the food for swallowing

Functions of saliva: ü Preparation lubrication. ü Solventü Help of the food for swallowing and Taste sensation. in speech. ü Digestion. ü Cleansing action. ü Regulation of water balance. ü Excretory function.

Applied aspects: 1. Xerostomia / Aptyalism: Complete absence of salivary secretion. Congenital absence of

Applied aspects: 1. Xerostomia / Aptyalism: Complete absence of salivary secretion. Congenital absence of salivary gland. 2. Sialorrhoea: Increase salivary secretion. Pregnancy, tumor of the gland.

3. Hypo secretion: Decrease in salivary secretion. Anxiety , Fear, Dehydration. 4. Chorda tympani

3. Hypo secretion: Decrease in salivary secretion. Anxiety , Fear, Dehydration. 4. Chorda tympani syndrome: Sweat secretion instead of salivary secretion while having food. Misdirected growth of the nerve to the sweat glands of submental region.

5. Mumps: Enlargement of the gland. Viral infection of the parotid gland. 6. Sailolithiasis:

5. Mumps: Enlargement of the gland. Viral infection of the parotid gland. 6. Sailolithiasis: Stone formation in the salivary gland/ducts.

7. Crocodile tears: Tear secretion instead of salivary secretion while having food. Misdirected growth

7. Crocodile tears: Tear secretion instead of salivary secretion while having food. Misdirected growth of the facial nerve to the Lacrimal gland.