REVISION DIFFERENT MYELOID STAGES Charecteristics of granulocyte granules

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REVISION

REVISION

DIFFERENT MYELOID STAGES

DIFFERENT MYELOID STAGES

Charecteristics of granulocyte granules. The colour of the letters is the same as that

Charecteristics of granulocyte granules. The colour of the letters is the same as that of the granules and the backgroung the colour of cytoplasm of the cell the granules are most prominant in.

Pronormoblast

Pronormoblast

Auer rods in promyelocytes of M 3

Auer rods in promyelocytes of M 3

Toxic granulation of neutrophil

Toxic granulation of neutrophil

orthochromic normoblast

orthochromic normoblast

A- Pronormoblast B- polychromatic normoblast C- orthochromic normoblast

A- Pronormoblast B- polychromatic normoblast C- orthochromic normoblast

Promonocytes (with a single fissure in the nucleus)

Promonocytes (with a single fissure in the nucleus)

b a A- neutrophilic metamyelocyte b- neutrophilic myelocyte

b a A- neutrophilic metamyelocyte b- neutrophilic myelocyte

Promonocytes (with a single fissure in the nucleus)

Promonocytes (with a single fissure in the nucleus)

b b c a A- Promonocyte B- orthochromic normoblast c- band neutrophil

b b c a A- Promonocyte B- orthochromic normoblast c- band neutrophil

Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L

Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L 2 type

basophilicnormoblasts

basophilicnormoblasts

b b b c a b b b a d b e f A-pronormoblast

b b b c a b b b a d b e f A-pronormoblast b- orthochromic normoblast C- neutrophilic myelocyte D- neutrophilic metamyelocyte E- band neutrophil F- segmented neutrophil

b a a b b A- Promonocyte B- myeloid cell (both are present in

b a a b b A- Promonocyte B- myeloid cell (both are present in M 4 leukemia

a b b a- polychromatic normoblast (megaloblast) b- orthochromic normoblast

a b b a- polychromatic normoblast (megaloblast) b- orthochromic normoblast

b a A- Promonocyte B- promyelocyte (M 4 leukemia)

b a A- Promonocyte B- promyelocyte (M 4 leukemia)

Different maturation stages of myeloid cell in M 2 leukemia.

Different maturation stages of myeloid cell in M 2 leukemia.

Pronormoblast

Pronormoblast

Different maturation stages of myeloid cell with M 2 leukemia.

Different maturation stages of myeloid cell with M 2 leukemia.

Myeloblasts from M 1 or M 0 Peroxidase will confirm diagnosis

Myeloblasts from M 1 or M 0 Peroxidase will confirm diagnosis

Myeloblasts from M 1 Auer rods confirm diagnosis of M 1 not present in

Myeloblasts from M 1 Auer rods confirm diagnosis of M 1 not present in M 0

basophilic myelocyte

basophilic myelocyte

Peroxidase negative , PAS positive blast cells Small cells of the same population, lymphoblasts

Peroxidase negative , PAS positive blast cells Small cells of the same population, lymphoblasts from L 1 type

Peroxidase negative , PAS positive blast cells Small cells of the same population, lymphoblasts

Peroxidase negative , PAS positive blast cells Small cells of the same population, lymphoblasts from L 1 type

Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L

Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L 2 type

Monocytic precursors of M 5 leukemia

Monocytic precursors of M 5 leukemia

Lymphoblasts of hairy cell leukemia (myelofibrosis)

Lymphoblasts of hairy cell leukemia (myelofibrosis)

Lymphoblasts of hairy cell leukemia (myelofibrosis)

Lymphoblasts of hairy cell leukemia (myelofibrosis)

Lymphoblasts of hairy cell leukemia (myelofibrosis)

Lymphoblasts of hairy cell leukemia (myelofibrosis)

Plasma cells of multiple myeloma (note the multinucleated cell)

Plasma cells of multiple myeloma (note the multinucleated cell)

PAS +ve lymphoblast from L 3 leukemia

PAS +ve lymphoblast from L 3 leukemia

Plasma cells of multiple myeloma (note the multinucleated cell)

Plasma cells of multiple myeloma (note the multinucleated cell)

Plasma cells of multiple myeloma (note the multinucleated cell)

Plasma cells of multiple myeloma (note the multinucleated cell)

Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L

Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L 2 type

Erythrophagocytosis

Erythrophagocytosis

Erythrophagocytosis

Erythrophagocytosis

LE cell

LE cell

a b d c e d d d A- Eosinophilic myelocyte B- Promyelocyte C-

a b d c e d d d A- Eosinophilic myelocyte B- Promyelocyte C- Basophilic normoblast D- Polychromayic normoblast E- Orthochromic normoblast

Eosinophilic myelocyte

Eosinophilic myelocyte

Basophilic metamyelocyte

Basophilic metamyelocyte

Lymphoblasts of hairy cell leukemia (myelofibrosis) The red stain is ACP +ve hairy cell

Lymphoblasts of hairy cell leukemia (myelofibrosis) The red stain is ACP +ve hairy cell

Eosinophilic metamyelocyte

Eosinophilic metamyelocyte

megakaryocyte

megakaryocyte

Segmented Basophil

Segmented Basophil

Promyelocytes with auer rod bundles from M 3

Promyelocytes with auer rod bundles from M 3

CD 41 +ve cells Megakaryoblast from M 7 leukemia

CD 41 +ve cells Megakaryoblast from M 7 leukemia

megakaryoblast

megakaryoblast

pronormoblasts

pronormoblasts

Erythroid prcusors from M 6 Leukemia

Erythroid prcusors from M 6 Leukemia

Myeloblast from M 1 MPO stain

Myeloblast from M 1 MPO stain

Different myeloid stages from M 2

Different myeloid stages from M 2

Different myeloid stages from M 2

Different myeloid stages from M 2

Different myeloid stages from M 2

Different myeloid stages from M 2

Promyelocytes with auer rod bundles from M 3

Promyelocytes with auer rod bundles from M 3

Different eythroid precursors in M 6 leukemia

Different eythroid precursors in M 6 leukemia

Non specific esterase +ve cells Monoblast From M 5

Non specific esterase +ve cells Monoblast From M 5

PAS +ve lymphoblast from L 1 leukemia

PAS +ve lymphoblast from L 1 leukemia

neutrophilic metamyelocyte and segmented neutrophil

neutrophilic metamyelocyte and segmented neutrophil