REVISION DIFFERENT MYELOID STAGES Charecteristics of granulocyte granules
- Slides: 67
REVISION
DIFFERENT MYELOID STAGES
Charecteristics of granulocyte granules. The colour of the letters is the same as that of the granules and the backgroung the colour of cytoplasm of the cell the granules are most prominant in.
Pronormoblast
Auer rods in promyelocytes of M 3
Toxic granulation of neutrophil
orthochromic normoblast
A- Pronormoblast B- polychromatic normoblast C- orthochromic normoblast
Promonocytes (with a single fissure in the nucleus)
b a A- neutrophilic metamyelocyte b- neutrophilic myelocyte
Promonocytes (with a single fissure in the nucleus)
b b c a A- Promonocyte B- orthochromic normoblast c- band neutrophil
Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L 2 type
basophilicnormoblasts
b b b c a b b b a d b e f A-pronormoblast b- orthochromic normoblast C- neutrophilic myelocyte D- neutrophilic metamyelocyte E- band neutrophil F- segmented neutrophil
b a a b b A- Promonocyte B- myeloid cell (both are present in M 4 leukemia
a b b a- polychromatic normoblast (megaloblast) b- orthochromic normoblast
b a A- Promonocyte B- promyelocyte (M 4 leukemia)
Different maturation stages of myeloid cell in M 2 leukemia.
Pronormoblast
Different maturation stages of myeloid cell with M 2 leukemia.
Myeloblasts from M 1 or M 0 Peroxidase will confirm diagnosis
Myeloblasts from M 1 Auer rods confirm diagnosis of M 1 not present in M 0
basophilic myelocyte
Peroxidase negative , PAS positive blast cells Small cells of the same population, lymphoblasts from L 1 type
Peroxidase negative , PAS positive blast cells Small cells of the same population, lymphoblasts from L 1 type
Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L 2 type
Monocytic precursors of M 5 leukemia
Lymphoblasts of hairy cell leukemia (myelofibrosis)
Lymphoblasts of hairy cell leukemia (myelofibrosis)
Lymphoblasts of hairy cell leukemia (myelofibrosis)
Plasma cells of multiple myeloma (note the multinucleated cell)
PAS +ve lymphoblast from L 3 leukemia
Plasma cells of multiple myeloma (note the multinucleated cell)
Plasma cells of multiple myeloma (note the multinucleated cell)
Peroxidase negative , PAS positive blast cells of the different populations, lymphoblasts from L 2 type
Erythrophagocytosis
Erythrophagocytosis
LE cell
a b d c e d d d A- Eosinophilic myelocyte B- Promyelocyte C- Basophilic normoblast D- Polychromayic normoblast E- Orthochromic normoblast
Eosinophilic myelocyte
Basophilic metamyelocyte
Lymphoblasts of hairy cell leukemia (myelofibrosis) The red stain is ACP +ve hairy cell
Eosinophilic metamyelocyte
megakaryocyte
Segmented Basophil
Promyelocytes with auer rod bundles from M 3
CD 41 +ve cells Megakaryoblast from M 7 leukemia
megakaryoblast
pronormoblasts
Erythroid prcusors from M 6 Leukemia
Myeloblast from M 1 MPO stain
Different myeloid stages from M 2
Different myeloid stages from M 2
Different myeloid stages from M 2
Promyelocytes with auer rod bundles from M 3
Different eythroid precursors in M 6 leukemia
Non specific esterase +ve cells Monoblast From M 5
PAS +ve lymphoblast from L 1 leukemia
neutrophilic metamyelocyte and segmented neutrophil