Regulating Cell Cycle Cells move through cycle at
- Slides: 16
Regulating Cell Cycle Cells move through cycle at different rates Muscle and nerve cells DO NOT DIVIDE! Bone marrow cells continuously make new blood cells Skin and digestive tract cells divide continuously Controls can be turned ON and OFF Regulatory proteins Protein CYCLIN regulates the cell cycle in eukaryotes
Regulatory Proteins Internal and External Growth factors stimulate growth and division of cells Embryonic development Wound healing
Apoptosis Cells are made; cells also die Cells may die by damage or programmed cell death APOPTOSIS starts series of steps that lead to cell self-destruction
CANCER is Uncontrolled Cell Growth Cancer cells do not respond to regulatory signals Uncontrolled division Tumor ~ mass of cancer cells Benign cells do NOT spread to nearby tissue or other parts of the body Malignant cells DO spread to other tissues and destroys them Cancer cells take nutrients from other cells, block nerves, disrupt organ function
Cancer Cell GROWTH Abnormal cell growth Tumor forms Cancer cells spread via bloodstream or lymph vessels
How Cancer Spreads
Possible causes of cancer Defective ‘cell growth and regulation’ genes Possible causes: Smoking, chewing tobacco (lungs, mouth) Radiation UV exposure (melanoma/skin cells) Defective genes, such as p 53 Heredity (genetic disposition) Viruses (HPV) Treatment: removal of cancer cells, radiation, pharmaceuticals (chemical compounds), gene therapy?
VIRUSES VIRUS ~ nonliving particle that can reproduce ONLY by infecting living cells Viruses ~ Latin for ‘POISON’ STRUCTURE OF VIRUS: Capsid ~ protein coat surrounding virus Allows virus to enter host cells by binding surface proteins DNA or RNA inside
Types of VIRUSES
VIRAL Replication
Types of viral replication Lytic infection ~ Virus enters bacterial cell, replicates, causes cell to burst (lyse) Lysogenic infection ~ Virus’s nucleic acid is inserted into host DNA RNA viruses ~ Common cold, HIV
Replication ~ FLU virus
Replication ~ HIV
Diseases caused by viruses
- 10-3 regulating the cell cycle
- 10-3 regulating the cell cycle
- Sport winners move backwards and losers move forward
- Piloerection
- Regulating body temperature
- Ogtt curve
- Regulating body temperature
- The process of evaluating and regulating ongoing activities
- Control valves ppt
- Cardiac output is determined by
- Fluid portion of blood in which blood cells move
- Events of the cell cycle
- Cell cycle and cell division
- Biology.arizona.edu/cell bio/activities/cell cycle/01.html
- Cell cycle phases
- Onodi cells
- Papillary duct of bellini