Regenerativna medicinaprilonost za podjetja Miomir Kneevi Nacionalni intitut

Regenerativna medicinapriložnost za podjetja? Miomir Knežević Nacionalni inštitut za biologijo www. nib. si miomir. knezevic@nib. si

Uporabljeni material: • Stem cells and the innovation process Global commercialisation of UK stem cell research Nicola Perrin: N. M. R. Perrin. 04@cantab. net – Dr Paul Martin Ian Bunker: – Institute for the Study Ian. bunker@uktradeinvest. gov. uk of Genetics, Biorisks and Society (IGBi. S) The Role of Technology Foresight in • University of Anticipating Global Technology Trend, Nottingham, UK Terutaka KUWAHARA, NISTEP

Ocene poslovnih priložnosti

Embrionalne matične celice Tkivno inženirstvo

Ne moreš graditi ugleda na tistem, kar šele nameravaš narediti Henry Ford

Uporaba nanotehnologije

Zakasnitveni čas od tehnološke realizacije do uporabe

Multidisciplinarno okolje – Vede o življenju postajajo center 2005 - 2015 -2025 Nanotechnology and material Manufacturing Industrial infrastructure Electronics Health, medical care and welfare Agriculture, forestry, fisheries and food Industrial infrastructure Science and technology for society Life sciences Environment Social infrastructure Health, medical care and welfare Information and communications Science and technology for society Electronics Nanotechnology and material Manufacturing Nanotechnology and material Energy and resources Information and communications Energy and resources Agriculture, forestry, fisheries and food Space, marine and earth science *1 Respondents chose at most three fields to cooperate. *2 Black arrow indicates that 30% to 50% of respondents. *3 Red arrow indicates that more than 50% of respondents. Social infrastructure

Po 2015 Sprememba vpliva “Ved o življenju” Pred 2015 Technology for measuring biological substances Bioinfomatics Nanobiology Basic research for new medical technologies Index povečanja znanja Basic research in drug development Brain generation and growth Understanding and treating brain conditions Controlling higher-order biological functions Higher-order brain functions Socialno-ekonomski pomen Regenerative medical science Environmental and ecological biology

Predvideni čas realizacije tehnologij – Vede o življenju Čas tehnološke realizacije Bioinformatics Controlling higher-order biological functions Basic research in drug development Technology for measuring biological substances Environmental and ecological biology Nanobiology Regenerative medical science Understanding and treating brain conditions Basic research for new medical technologies Čas uporabe v praksi

Najpomembnejše tehnologije na področju Ved o življenju : Študij možganov “Top 10” : Nove medicinske tehnologije in zdravila : Regenerativna medicina Topic Area Effective technology to prevent cancer metastasis. Basic research for new medical technologies 2020 / 2030 Technology for immediate, complete control of allergies based on elucidation of the immunoregulatory mechanisms and environmental factors that lead to hay fever, atopic dermatitis, and other allergies. Treatment for preventing the progression of Alzheimer's disease. Basic research for new medical technologies 2015 / 2027 Understanding and treating brain conditions Technology for measuring biological substances Understanding and treating brain conditions 2019 / 2030 Basic research in drug development 2015 / 2026 Environmental and ecological biology Regenerative medical science Basic research for new medical technologies 2014 / 2024 Elucidation of the etiology of manic-dpressive psychosis at the molecular level. Technology to detect a cancerous tissue of the diameter smaller than 1 mm presenting anywhere in the body. Elucidation of the etiology of schizophrenia at the molecular level. Technologies for drug development to predict bioactivities of proteins such as interactions between protein and protein, between proteins and DNA or RNA, and between proteins and synthetic compounds from their higher order structure. Mass production technology for fuels and bioplastics utilizing plants and microorganisms. Technology to manipulate stem cell differentiation and growth for induction of functional cells to use for therapy. Effective cancer prevention measures can be implemented by clarifying the relationships among multiple environmental risk factors associated with cancer. Year 2020 / 2014 / 2023 2022 / - 2016 / 2029 2020 / 2030

Tehnološka pot Regenerativna medicina Razvoj osnivne tehnologije Izdelava umetnih organov

Timescale for commercial opportunities Therapeutics Value Research applications Enabling technologies Cell therapies Growth factors Manufacturing Drug screening Toxicity testing Research tools Clinical trials Training 20 5 Cell banking 10 15 Time (years)

Translation of stem cell research into commercial products Stopnje: Applied Development Basic Research Clinical Therapies Manufacturing Infrastruktura : Universities, Research Institutes Biotech SMEs Pharma Clinicians Deležniki: Government / regulatory agencies Financiranje: ? ? Research Councils Charities Commercial funding VC, pharma Funding Gap

Noben uspeh ni dokončen, nobena napaka ni nepopravljiva: šteje le pogum, da nadaljuješ. Winston Churchill