PYRAMID POINTS CHAPTER 70 IMMUNOLOGICAL MEDICATIONS PYRAMID POINTS
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PYRAMID POINTS CHAPTER 70: IMMUNOLOGICAL MEDICATIONS
PYRAMID POINTS I. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome Medications include nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, nucleotide reverse transcriptase inhibitors, protease inhibitors, fusion inhibitors Ø Other medications include those used to treat complications such as opportunistic infections Ø Nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, nucleotide reverse transcriptase inhibitors inhibit activity of reverse transcriptase Ø ADULT HEALTH: Immunological Medications Elsevier items and derived items © 2008 by Saunders, an imprint of Elsevier Inc. 2
PYRAMID POINTS I. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome (continued) Protease inhibitors interfere with activity of protease enzyme Ø Fusion inhibitors inhibit binding of HIV to cells Ø Anti-inflammatory medications Ø Anti-infective medications Ø Antifungal medications Ø Antiviral medications Ø ADULT HEALTH: Immunological Medications Elsevier items and derived items © 2008 by Saunders, an imprint of Elsevier Inc. 3
PYRAMID POINTS II. Systemic Lupus Erythematosus Ø Description • Medications are used to decrease pain and inflammatory response Azathioprine (Imuran) Ø Cyclophosphamide (Cytoxan) Ø Hydroxychloroquine sulfate (Plaquenil) Ø Prednisone (Deltasone) Ø Nonsteroidal anti-inflammatory drugs Ø ADULT HEALTH: Immunological Medications Elsevier items and derived items © 2008 by Saunders, an imprint of Elsevier Inc. 4
PYRAMID POINTS III. Immunizations (Refer to Module 47 for information about immunizations) ADULT HEALTH: Immunological Medications Elsevier items and derived items © 2008 by Saunders, an imprint of Elsevier Inc. 5
PYRAMID POINTS IV. Immunosuppressants Ø Description • Used for transplant clients to prevent organ or tissue rejection and to treat autoimmune disorders such as systemic lupus erythematosus Ø Ø Ø Ø Ø Cyclosporine (Sandimmune, Neoral, Gengraf) Azathioprine (Imuran) Basiliximab (Simulect) Daclizumab (Zenapax) Muromonab-CD 3 (Orthoclone OKT 3) Mycophenolate mofetil (Cell. Cept) Sirolimus (Rapamune) Tacrolimus (Prograf) Cyclophosphamide (Cytoxan, Neosar) Methotrexate (Rheumatrex, Trexall) ADULT HEALTH: Immunological Medications Elsevier items and derived items © 2008 by Saunders, an imprint of Elsevier Inc. 6
The client with acquired immunodeficiency syndrome (AIDS) and Pneumocystis jiroveci infection has been receiving pentamidine (Pentam 300). The nurse assisting in caring for the client monitors the client most closely for signs of: 1. 2. 3. 4. Nausea Restlessness Fatigue Infection ADULT HEALTH: Immunological Medications Elsevier items and derived items © 2008 by Saunders, an imprint of Elsevier Inc. 7
