PTT 403 Biotechnology Products Commercialization Review on Malaysia
PTT 403 - Biotechnology Products Commercialization Review on Malaysia Potential to Commercialize Biotechnology Products
Government Agenda in Biotech • Malaysia has adopt Biotechnology as one of economic driver. • In 2005, Malaysia launched National Biotechnology Policy which highlighted 9 area that will given priority. • Malaysian Biotech Sdn Bhd is among bodies established to initiate biotechnology activities in Malaysia.
Why Malaysia Can Success in Biotechnology Field 1. Malaysia has the rainforest - Many species are still unexplored - Plants are sources of useful compounds - Example, about 70% of all new-cancer compounds came from rainforests and only 1% of these have actually been fully studied.
NATIONAL BIOTECHNOLOGY POLICY The Malaysian Government commits itself to undertake the role of developer and catalyst of the country’s biotechnology sector Launched in 2005 and the Malaysian Biotechnology Corporation Sdn Bhd (Biotech. Corp) was set up as a dedicated agency to drive this policy.
The 9 Thrusts of National Biotechnology Policy 1. Agricultural Enhance the value creation of the agricultural sector. 2. Healthcare Commercialising the discoveries of health related natural products and bio-generic drugs. 3. Industrial Increase opportunities in bio-processing and biomanufacturing
4. Research & Development Establish centres of biotechnology excellence, through research and development. 5. Human Capital Development Build the nation’s human capital through education, training and research activities. 6. Financial Infrastructure Provide the right financial support via competitive lab to market funding and incentives.
7. Legal & Regulatory Framework Reviewing ownership of intellectual properties and regulations relating to biotechnology processes and business. 8. Strategic Development Build international recognition for Malaysian biotechnology. 9. Government Support & Commitment Dedicated and professional Government agency to spearhead the development of the biotechnology industry with the incorporation of Biotech. Corp.
NATIONAL BIOTECHNOLOGY POLICY PHASE 1 2005 § § § § Capacity Building Establishment of advisory and implementation Councils Establishment of Malaysian Biotechnology Corporation Education and training of knowledge workers Development of legal and IP framework Business development through Accelerator Programmes Build Malaysian Branding Initial job and industry creation in agricultural biotech, healthcare biotech, industrial biotech and bio-informatics 2010
NATIONAL BIOTECHNOLOGY POLICY PHASE 2 2011 Science to Commercialization § Develop expertise in drug discovery and development based on natural resources § § § New Products Development Technology Acquisition Intensify investment promotion Strengthen branding Develop capability in technology licensing Knowledge-intensive jobs creation 2015
NATIONAL BIOTECHNOLOGY POLICY PHASE 3 2016 Globalization 2020 § Consolidate strengths and capabilities in technology development § Further develop expertise and strength in drug discovery and development § Strengthen innovation and technology licensing § Promote global Malaysian companies
Why Malaysia Can Success in Biotechnology Field
Why Malaysia Can Success in Biotechnology Field 1. Malaysia has the rainforest - Many species are still unexplored - Plants are sources of useful compounds - Example, about 70% of all new-cancer compounds came from rainforests and only 1% of these have actually been fully studied.
2. Existing Agriculture base - Malaysia has long engagement to agricultural sector. - There are biotech based institutions and universities that conduct success biotech based research. - Example, institutes dedicated to rubber and palm oil research are unique in the world.
3. Grants and Venture Capital Funding Increase - More venture capitalists have become interested to invest in Malaysia. - Real success in pharmaceuticals, for example have inspired fund and grant manager. - In Malaysia, there are nearly 50 venture capital firms (2005) and still increasing.
4. Proven ICT Infrastructure and Experience in Hightech Industry - Malaysia’s ICT infrastructure has impressive expansion from Multimedia Super Corridor project. - Biotechnology relies heavily on IT because all quality biotech work is driven by high performance computing and highly intelligent networks and software. Example, bioinformatics.
5. Malaysia Government Commitment - The Malaysian government recognizes the importance of biotechnology industry and its significance to the economy in the 21 st century. - The government pledges to take a proactive role in the development of biotechnology industry through public awareness, education, R&D and trade.
Importance and Advantages of Biotechnology Products Through Bioeconomy
Pharmaceutical Products By Biotechnology Products Year Produced Interferon 1980 Insulin 1982 Vaksin Hepatitis B erythropoietin 1986 1989 Antihemofilik VII factor Albumin Serum 1990 - Modified Features Gen interferon was inserted into bacteria by recombinant DNA technology. Gen insulin was inserted into bacteria by recombinant DNA technology. Gen vaccine was inserted into yeast by recombinat technology. Gen responsible for the production of erythropoietin was inserted into bacteria by recombinant technology. Penggunaan teknologi DNA rekombinan digunakan dalam menghasilkan protein ini. Gen responsible for the production of albumin serum was inserted into bacteria by recombinant technology. Uses To help immune system react towards virus attack in cell/ to trigger the protective defenses of the immune system To supply insulin for diabetis melitus patient. To treat hepatitis B patient that can cause damage in liver. To stimulate production of red blood cell for anemia patient. Produced protein that needed by the blood to stop bleeding from surgery or injury. Used by burn victims, malnutrition, diarrhoea and liver or kidney failure.
So, what makes traditional pharmaceutical products difference from biopharmaceutical products?
Importance 1. Over the past two decades, countries across the globe have substantially increased their economic outputs in an environmentally conscious manner through commercial applications of biotechnology and life sciences. 2. A bioeconomy is the sustainable production of renewable biological resources.
Importance 3. the bioeconomy benefits society via breakthroughs in agricultural productivity, discoveries in healthcare and the adoption of sustainable industrial processes, while helping to meet the most pressing global challenges, such as increasing global populations, food scarcity, the depletion of fossil fuels and natural resources, and tightening environmental pressures and climate change.
The 10 shortlisted EPPs include industrial bio inputs, biochemicals, biomaterials, bio-based farm inputs, high value bioingredients, high value food varieties, biosimilars, drug discovery, molecular screening, as well as stem cells and regenerative medicine in Malaysia. However, the number of EPPs under the BTP is expected to increase as new biotechnology projects are identified.
20 Bioeconomy Trigger Projects
NEW BIOTECHNOLOGY • 1. plant biotechnology for manufacturing recombinant pharmaceuticals (molecular pharming • plant molecular pharming represented a highly novel and potentially disruptive manufacturing technology for recombinant proteins
- Slides: 25