Protein unfolding strongly modulates the allergenicity and immunogenicity

  • Slides: 13
Download presentation
Protein unfolding strongly modulates the allergenicity and immunogenicity of Pru p 3, the major

Protein unfolding strongly modulates the allergenicity and immunogenicity of Pru p 3, the major peach allergen Masako Toda, Ph. D, Gerald Reese, Ph. D, Gabriele Gadermaier, Ph. D, Veronique Schulten, MSc, Iris Lauer, Ph. D, Matthias Egger, Ph. D, Peter Briza, Ph. D, Stefanie Randow, Sonja Wolfheimer, Valencia Kigongo, BSc, Maria del Mar San Miguel Moncin, MD, Kay Fötisch, Ph. D, Barbara Bohle, Ph. D, Stefan Vieths, Ph. D, Stephan Scheurer, Ph. D Journal of Allergy and Clinical Immunology Volume 128 Issue 5 Pages 1022 -1030. e 7 (November 2011) DOI: 10. 1016/j. jaci. 2011. 04. 020 Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI:

Fig 1 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI:

Fig 2 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI:

Fig 3 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI:

Fig 4 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 5 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI:

Fig 5 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 6 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI:

Fig 6 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 7 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI:

Fig 7 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 8 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI:

Fig 8 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E 1 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7

Fig E 1 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E 2 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7

Fig E 2 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E 3 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7

Fig E 3 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E 4 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7

Fig E 4 Journal of Allergy and Clinical Immunology 2011 1281022 -1030. e 7 DOI: (10. 1016/j. jaci. 2011. 04. 020) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Allergenicity and Crosssensitization Crossreactivity Allergenicity Capacity of anAllergenicity and Crosssensitization Crossreactivity Allergenicity Capacity of an
Nlinked glycosylation modulates the immunogenicity of recombinant humanNlinked glycosylation modulates the immunogenicity of recombinant human
PROTEIN OUTLINE Protein Definition Protein structure Protein FunctionPROTEIN OUTLINE Protein Definition Protein structure Protein Function
Protein Simple Protein Conjugated Protein Derivative Protein SpecialProtein Simple Protein Conjugated Protein Derivative Protein Special
Protein Yaps Analizi Protein aileleri Protein lokalizasyonu proteinProtein Yaps Analizi Protein aileleri Protein lokalizasyonu protein
Protein Stability Protein Folding Protein Stability Protein stabilityProtein Stability Protein Folding Protein Stability Protein stability
Safety and Immunogenicity Study of Rabies G ProteinSafety and Immunogenicity Study of Rabies G Protein
Strongly connected components 1 Strongly connected components DefinitionStrongly connected components 1 Strongly connected components Definition
FRONT OF ROOM STRONGLY AGREE STRONGLY DISAGREE TFRONT OF ROOM STRONGLY AGREE STRONGLY DISAGREE T
Strongly Agree Disagree Strongly Disagree Four Corners WhenStrongly Agree Disagree Strongly Disagree Four Corners When
MONEY BUYS HAPPINESS Strongly Agree Disagree Strongly DisagreeMONEY BUYS HAPPINESS Strongly Agree Disagree Strongly Disagree
Strongly Disagree to Strongly Agree Scale of 1Strongly Disagree to Strongly Agree Scale of 1