Prostate Pathology Part 1 Francisco G La Rosa
- Slides: 57
Prostate Pathology Part 1 Francisco G. La Rosa, MD Associate Professor, Department of Pathology University of Colorado Denver, Aurora, Colorado
NORMAL ANATOMY
SAGITAL SECTION OF THE PROSTATE GLAND Seminal Vesicle Central Zone Bladder Peri-urethral zone Transition Zone Peripheral Zone Anterior Zone Fibro-muscular Urethra
3 D VIEW OF THE PROSTATE
3 D VIEW OF THE PROSTATE
CROSS SECTION OF THE PROSTATE FIBROMUSCULAR STROMA anterior PERI-URETHRAL STROMA EJACULATORY DUCTS
TRANZITIONAL ZONE Urethra Seminal Vesicle
CENTRAL ZONE
Peripheral Zone
Fibro-muscular Stroma anterior
HISTOLOGY
Bad Histology
Peripheral Zone
Central Zone
Central Zone
Central Zone
Central Zone
Central Zone
40 X Seminal Vesicles
20 X Seminal Vesicles
20 X Seminal Vesicles
Paraganglion
40 X Neurons
Benign Lesions
Inflammation
Acute Inflammation
Acute Inflammation
Acute Inflammation
Acute Inflammation
Granuloma
20 X Corpora Amylacea
20 X Corpora Amylacea Calcified
200 X Cristalloid
200 X Stromal Nodules
H Y P E R P L A S I A
PRIMARY NODULAR HYPERPLASIA
BENIGN NODULAR HYPERPLASIA Usual Patterns Cell Type Special Patterns Mesenchymal Predominantly stromal Mixed Predominantly glandular Fibroblast Smooth Muscle Leiomatous Hyperplasia Basal Cells Basal Cell Hyperplasia Secretory Cells Crybiform Hyperplasia Small Cell Hyperplasia
BENIGN NODULAR HYPERPLASIA
BENIGN NODULAR HYPERPLASIA
BPH & Inflammation
BPH & Inflammation
BASAL CELL HYPERPLASIA
200 X BASAL CELL HYPERPLASIA
200 X BASAL CELL HYPERPLASIA
BASAL CELL HYPERPLASIA - HMWCK
ATROPHY
20 X SIMPLE ATROPHY
200 X ATROPHY
40 X ATROPHY
10 X CYSTIC ATROPHY
PIN Prostatic Intraepithelial Neoplasia
Prostatic Intraepithelial Neoplasia Mild Secretory cells Carcinoma Dysplasia Lumen Moderate Severe In situ Microinvasive Normal Basal Cells Basal Membrane Low Grade High Grade Prostatic Intra-epithelial Neoplasia
Prostatic Intra-epithelial Neoplasia
Prostatic Intra-epithelial Neoplasia
Prostatic Intra-epithelial Neoplasia
It continues in Part 2