Production of the effector cytokine interleukin17 rather than Slides: 5 Download presentation Production of the effector cytokine interleukin-17, rather than interferon-γ, is more strongly associated with autoimmune hemolytic anemia by Andrew M. Hall, Omar M. Zamzami, Natasha Whibley, Daniel P. Hampsey, Anne M. Haggart, Mark A. Vickers, and Robert N. Barker haematol Volume 97(10): 1494 -1500 October 9, 2012 © 2012 by Ferrata Storti Foundation Serum IFN-γ and IL-17 levels in patients with AIHA compared to those in healthy donors Levels of IFN-γ and IL-17 A were measured in serum samples taken from patients with AIHA (n=20) and matched healthy control donors (n=19). Andrew M. Hall et al. Haematologica 2012; 97: 1494 -1500 © 2012 by Ferrata Storti Foundation Relationships between degree of anemia and serum IFN-γ and IL-17 concentrations in patients with AIHA. The concentrations of serum IFN-γ (n=11) and IL-17 A (n=19) in patients with AIHA were compared to hemoglobin levels at the time of blood donation as an in. . . Andrew M. Hall et al. Haematologica 2012; 97: 1494 -1500 © 2012 by Ferrata Storti Foundation Production of IFN-γ and IL-17 in response to autologous RBC by T cells from AIHA patients and healthy control donors. Andrew M. Hall et al. Haematologica 2012; 97: 1494 -1500 © 2012 by Ferrata Storti Foundation Production of IFN-γ and IL-17 in response to Rh. D autoantigen by T cells from AIHA patients. Andrew M. Hall et al. Haematologica 2012; 97: 1494 -1500 © 2012 by Ferrata Storti Foundation Cytokine effectsProses productionSensor integrator effectorHow a light sensor worksEffector cells in nervous systemImmune effector cells