Prisma Plus Film Competitor integrated systems Competitor Analysis

Prisma Plus & Film Competitor

integrated systems

Competitor Analysis – Leica Histocore Spectra Workstation Unique to Prisma Plus & Film Unique to Histocore Spectra Workstation Common to Both Throughput 360 slides(Prisma Plus) & 1, 090 slides(Film) per hour Throughput 330 slides per hour Open system Integrate with a film coverslipper Throughput on validated H&E kit 240 slides per hour Patient slides submerged in shared reagents Reagent grouping Provides customer list (partial) Stainer can interface to a specimen-tracking system Continuous slide loading 6 racks in oven Continuous agitation Touch screen H&E and special stains Open barcode reader Onboard automated single slide counting Coverslipper integrated to LIS or T&T Protocol autostart by color coded racks with RFID technology Multiple runs simultaneously 12 basket coverslipper storage station Dual robotic arm Remote support and updates Low slide drying time (cs) Ready to use H&E kit with RFID technology for accurately tracks reagent usage, slide volume and maintain records. PE station provides ability to do Mega Slide staining Automatic fill level scan which you have to start manually Up to 50 different reagent containers Oven operation is fixed time of 15 min. This cannot be altered. Customer can choose to use the oven or not in the protocol Multiple staining reservoir configurations Validated HE kit Oven for special stains 50 programs/protocols Glass-slide drying time of 5 minutes due to integrated coverslipper oven 36 ‘cuvette’ stations, volume if 380 m. L + 6 Wash + 5 input/output Up to 11 simultaneous runs Glass detection sensor that automatically removes and transfers broken coverslips Programmable end station Coverslipper with 9 rack output drawer with a capacity of 270 slides Standard and mega slides 3 Reagent Management Method (manually) in terms of runs, days, slides Up to 5 start stations Integrate with a glass coverslipper

Competitor Analysis – Leica ST 5020 Unique to Prisma Plus & Film Unique to ST 5020 Multistainer Common to Both Throughput 360 slides(Prisma Plus) & 1, 090 slides(Film) per hour Capacity of 12 racks of 30 slides = 360 slides Open system Capacity of 660 slides RTU reagents (Selec. Tech) H&E and specials User programmable Link with Film coverslipper or glass coverslipper automated program assignment and start (Code. Rack) Touchscreen On demand loading of the coverslipper whilst stainer in operation Glass coverslipper only Continuous slide loading 12 basket coverslipper storage station 36 stations and 4 ovens LIS connecteable Reagent grouping Standard installation and basic training in 3 hours Customisable with ovens and heating stations Fast slide drying time (Film) Programmable Start/Finish PE station provides ability to do Mega Slide staining H&E and Specials on same system Multiple staining reservoir configurations Oven for special stains Up to 11 simultaneous runs Programmable end station Up to 5 start stations 4 Slide rack suited for certain scanners 4

Competitor Analysis – DAKO Coverstainer Unique to Prisma Plus & Film Unique to Dako Coverstainer Common to Both Throughput 360 slides(Prisma Plus) & 1, 090 slides(Film) per hour Throughput to 240 slides/hr Onboard drying system Overnight run 660 slides 240 coverslipped Overnight run 240 of which 120 coverslipped Touchscreen H&E and Specials on same system Staining host computer can be interfaced to an LIS Barcode reader Integrated Film Coverslipper (or glass) Stainer can interface to a specimen-tracking system User programmeable, 50 vs 19 prototocols Open reagent system Combination of open and closed system LIS connecteable 2 drying ovens Full automation of entire H&E process Continuous loading Multiple staining reservoir configurations 3 pre-optimised protocols Oven for special stains TU kits Up to 11 simultaneous runs Programmable end station Up to 5 start stations 12 basket coverslipper storage station On demand loading of the coverslipper Reagent grouping High reliability Low slide drying time PE station allows Mega Slide staining 5 Slide rack suited for certain scanners

Competitor Analysis – ROCHE Ventana HE 600 Unique to Prisma Plus & Film Common to Both Throughput 360 slides(Prisma Plus) & 1, 090 slides(Film) per hour Throughput 200 per hour? Touchscreen Dip and Dunk proven technology Single slide staining technology Continuous slide loading Open reagent system Programmable Start/Finish H&E Configurable with a film coverslipper or glass coverslipper Staining host computer can be interfaced to an LIS H&E and Special stains on same system Closed system User programmable Stainer can interface to a specimen-tracking system 2 drying ovens One- and two-dimensional open barcode 12 basket coverslipper storage station Xylene free Et. OH free Integrated Film Coverslipper H&E and Specials on same system Multiple staining reservoir configurations Oven for special stains Up to 11 simultaneous runs Programmable end station On demand loading of the coverslipper 6 Unique to Ventana HE 600 Reagent grouping High reliability and suipport teams Glass coverslipper integrated

Non integrated systems

Competitor Analysis – LEICA ST 5010 Autostainer Unique to Prisma Plus & Film Common to Both Throughput 360 slides(Prisma Plus) & 1, 090 slides(Film) per hour Throughput? Continuous slide loading Open barcode reader (c/s) 2, 500 H&E slides 1 reagent/ test kit can handle Stainer can interface to a specimen-tracking system Configurable with a film coverslipper or glass coverslipper Standard installation and basic training in 3 hours Onboard drying system 2 drying ovens Open reagent system Touchscreen Patient slides submerged in shared reagents On demand loading of the coverslipper whilst stainer in operation User programmable Coverslipper intergated to LIS or T&T Can be integrated into Coverslipper 12 basket coverslipper storage station Reagent grouping (e. g HX) Low slide drying time (cs) PE station provides ability to do Mega Slide staining i. Support 8 Unique to LEICA ST 5010 Autostainer

Competitor Analysis – Thermo Gemini Unique to Prisma Plus & Film Common to Both Throughput 360 slides(Prisma Plus) & 1, 090 slides(Film) per hour Throughput Open system Integrate with a film coverslipper or glass coverslipper set by manufacturer or user programmable (user’s choice) Patient slides submerged in shared reagents Provides customer list (partial) Stainer can interface to a specimen-tracking system Open barcode reader Coverslipper intergated to LIS or T&T 12 basket coverslipper storage station Reagent grouping (e. g HX) Low slide drying time (cs) PE station provides ability to do Mega Slide staining Up to 50 different reagent containers Multiple staining reservoir configurations Oven for special stains 9 Unique to Thermo Fisher Gemini AS Up to 11 simultaneous runs Programmable end station Up to 5 drying stations Continuous slide loading Onboard quality control Touch screen Small footprint H&E and special stains Standard and mega slides

Competitor Analysis – Medite TST 44 Unique to Prisma Plus & Film Unique to Medite TST 44 Common to Both Integrated with a film- or glass coverslipper Programmable Start/Finish Provides customer list (partial) Throughput up to 530 slides per hour Throughput up to 500 slides per hour Open reagent system Stainer can interface to a specimen-tracking system Configurable with a glass coverslipper Open barcode reader Onboard quality control Touchscreen Loading and unloading without robotic movement Total time for standard installation and basic training in 1 day H&E and Specials on same system 6 waterstations Continuous loading Multiple staining reservoir configurations 20 programs/protocols 2 drying systems Oven for special stains 12 programs in parallel Coverslipper intergated to LIS or T&T 12 basket coverslipper storage station Reagent grouping Low slide drying time (cs) PE station provides ability to do Mega Slide staining 50 Reagent colour codings possible Programmable end station 1 0 Up to 5 start stations

Competitor Analysis – VWR SHURstainer 3030 Unique to Prisma Plus & Film Throughput 360 slides(Prisma Plus) & 1, 090 slides(Film) per hour Stainer can interface to a specimen-tracking system Open barcode reader 2 drying ovens Configurable with a film coverslipper or glass coverslipper Continuous slide loading 1 1 Unique To VWR SHURstainer 3030 Staining host computer can be interfaced to an LIS Batch and continuous load (30 slides per rack/3 racks per run) Set by manufacturer or user programmable (user’s choice) Total time for standard installation and basic training in 3 hours Common to Both H&E and special stains Open system for reagents Standard installation and basic training in 1 day 50 programs Touch screen

Competitor Analysis – LEICA ST 4020 Unique to Prisma Plus Throughput 360 slides(Prisma Plus) per hour integration with a film or glass coverslipper H&E and specials Provides customer list (partial) Stainer can interface to a specimen-tracking system Batch and continuous load (20 slides per rack/3 racks per run) 2 drying ovens Open barcode reader 1 2 Unique to LEICA ST 4020 Throughput ? Set by manufacturer or user programmable (user’s choice) Standard installation and basic training in 3 hours small (50 -m. L) container for reagent savings, 4 slides carriers Common to Both Open system Dip and Dunk technology

Competitor Analysis – Leica Histocore Spectra ST Unique to Prisma Plus & Film Throughput 360 slides(Prisma Plus) & 1, 090 slides(Film) per hour Integrate with a film coverslipper or glass coverslipper Unique to Histocore Spectra ST Throughput up to 330 H&E slides/hour set by manufacturer or user programmable (user’s choice) Common to Both Open system Patient slides submerged in shared reagents Reagent grouping 6 heated/drying ovens Continuous slide loading Provides customer list (partial) 5 rack load / start stations Touch screen Stainer can interface to a specimen-tracking system Continuous agitation H&E and special stains Open barcode reader Onboard automated single slide counting Up to 5 start stations Coverslipper intergated to LIS or T&T Protocol autostart by color coded racks with RFID technology Multiple runs simultaneously 12 basket coverslipper storage station Dual robotic arm Remote support and updates Low slide drying time (cs) Ready to use H&E kit with RFID technology for accurately tracks reagent usage, slide volume and maintain records. PE station provides ability to do Mega Slide staining Automatic fill level scan which you have to start manually Up to 50 different reagent containers Multiple staining reservoir configurations Oven for special stains 50 programs/protocols Up to 11 simultaneous runs Programmable end station 1 3 and mega slides Standard Reagent Management Method (manually) in terms of runs, days, 52 reagent cuvette stations of 380 m. L

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