Premotor cortex Damage to descending motor pathways Friday
- Slides: 10
Premotor cortex Damage to descending motor pathways Friday Jan. 27 03 -55 -485 1
Friday Jan. 27 03 -55 -485 2
Premotor cortex -movement selection • Reciprocal connections • with the primary motor cortex • And project axons through corticobulbar and corticospinal pathways • Uses information from other cortical regions • Active during association of visual (sensory) to movement. Friday Jan. 27 03 -55 -485 3
Lateral premotor cortex • Cell activity associated with movement in a particular direction. • For conditional motor tasks, cells become active at the appearance of a cue. • Before the signal to make the movement Friday Jan. 27 03 -55 -485 4
Lateral premotor cortex • Encode a monkey’s intention to perform a particular movement. • Involved in the selection of movements based on external events. Friday Jan. 27 03 -55 -485 5
Lateral premotor cortex • If lesioned – --> monkey has difficulty performing visually cued conditional tasks. Friday Jan. 27 03 -55 -485 6
Lateral premotor cortex • Patients with frontal lobe damage: – Difficulty learning to select a particular movement to be performed in response to a visual cue. Friday Jan. 27 03 -55 -485 7
Medial premotor cortex • Mediates internal cues to movement initiation. • f. MRI scans in humans: activated when subjects perform movements from memory. Friday Jan. 27 03 -55 -485 8
Damage to descending motor pathways • Upper Motor Neuron Syndrome – Damage to cortex or anywhere along the descending tracts – --> muscles contralateral side become flaccid on limbs and face. – Brainstem preserves trunk muscles Friday Jan. 27 03 -55 -485 9
Babinski sign • Maturation of corticospinal pathway • An indicator of damage to descending upper motor neuron pathways. Friday Jan. 27 03 -55 -485 10