Preliminary Work and Proposed Continuation Imaging of Speech

Preliminary Work and Proposed Continuation: Imaging of Speech Anatomy and Behavior Speech Surgery Mark Hasegawa-Johnson Lynn Grames David Kuehn Jerry Moon Jeff Marsh MRI Zhi-Pei Liang Victor Schepkin Thomas Conturo Nikolaos Tsekos Jeff Tsao Finite Elements Fariborz Alipour Reiner Wilhelms-Tricarico Statistics Xuming He

Outline } Clinical Objectives } Speech Posture } Lingual Anatomy } Speech Kinematics

Clinical Objective: Surgical Planning Kacker, 2000 Beckwith-Wiedemann Syndrome } Normal intelligence, personality. } At least 9 published resection methods; no quantitative comparison of results.

Finite Element Modeling of the Tongue Wilhelms-Tricarico, 1995, 2000 Objective of Proposed Preliminary Study: Simulate effects of two common surgeries. Limitation: detailed knowledge of structure & biomechanical properties.

Normative Data: Speech Posture Hasegawa-Johnson et al. , http: //www. ifp. uiuc. edu/speech/mri } Purpose: Normative data for articulatory therapy, speech synthesis, speech science. } 3 mm Multislice, 750 ms/image, 25 seconds breath hold.

Normative Data: Speech Posture Hasegawa-Johnson and Zheng, ASHA Leader 5(16): 144 Zheng, Hasegawa-Johnson, and Pizza, in review PARAFAC analysis of 3 D tongue shape ==> Talkerindependent vowel space

Dimensions of the talkerindependent vowel space: 1: grooved back lowering (/a/), 2: flattened front lowering (/E/).

Normative Data: Speech Posture Hasegawa-Johnson, Pizza, et al. , in review More details: Near constriction: talkerindependent oral area. Elsewhere: oral area proportional to palate height.

Lingual Anatomy 3 D Anatomical Image, 1 mm voxel: Conturo, 9/2001

Lingual Anatomy: Microstructure Cadaver sample, 59 micron voxel: Schepkin, 12/2001

Lingual Anatomy: Diffusion Tensor MRI of Human Brain: Conturo et al. , 1999

Speech Kinematics: Tagged MRI Stone et al. , 2001: Gated imaging, “ka” } Purpose: Direct observation of biomechanical quantities. } Limitation: 32 repetitions per image sequence.

Speech Kinematics: Real-Time Simulated BLAST real-time imaging: Tsao, 2000

Real-Time tagged MRI using Harmonic Phase Imaging (HARP) Simulated HARP of tongue: Hasegawa-Johnson, 2002

Conclusions } Speech Science Research Issues } Muscle fiber organization } Strain dynamics of soft tissue } Clinical Applications } Surgical planning } Diagnosis of biomechanical defects } Difficult Imaging Problems } Segmentation of inter-muscle boundaries } High-speed dynamic imaging