Potassium and Membrane Pumps Potassium and Membrane Pumps

Potassium and Membrane Pumps

Potassium and Membrane Pumps POTASSIUM Avocado 38. 1 m. Eq vs. Banana 11. 6 m. Eq Sperm 7% US RDA potassium vs. Asparagus 4% US RDA Serum K+: 3. 5 – 5. 0 m. M; 97% of the body’s K+ is intracellular

Potassium and Membrane Pumps JACK KEVORKIAN DR. DEATH “When society reaches the age of enlightenment, then they’ll call me Dr. Life” Assisted 130 people over 10 years to kill themselves Narcotic plus a lethal dose of KCl

Potassium and Membrane Pumps NERNST EQUILIBRIUM POTENTIAL IV 100 mg/Kg is a lethal dose DEATH BY DEPOLARIZATION

Potassium and Membrane Pumps DIGITALIS: CARDIAC GLYCOSIDES Dried leaf of the foxglove plant Digitalis purpurea Squill: ancient Egyptians and Romans Tipped poison arrows Witches' glove, Dead Man's Bells, Bloody Fingers Modern Therapy: CONGESTIVE HEART FAILURE

Potassium and Membrane Pumps Na+/K+ ATPase A Binding inhibits nucleotide hydrolysis

Potassium and Membrane Pumps

Potassium and Membrane Pumps DIGOXIN TOXICITY The foxglove when give in very large and quickly repeated doses, occassions sickness, vomiting, purging, giddiness, confused vision and objects appearing W. Withering, 1785 Vision is often also blurred. White borders or halos may appear on dark objects and objects may appear frosted. Color vision can be disturbed; chromatopsia is most common for yellow and green but less frequently red, brown and blue vision can occur.

Potassium and Membrane Pumps