Polysaccharase Laccase Protease Lipase Extremozymes Enzyme in biotechnology

海洋微生物酵素 • • • Polysaccharase Laccase Protease Lipase Extremozymes Enzyme in biotechnology Restriction enzyme Other nuclease Bacteriolytic enzymes from phage

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Laccase漆酶 • Laccases (EC 1. 10. 3. 2) are coppercontaining oxidase enzymes that are found in many plants, fungi, and microorganisms • Application in industry and food

DNA polymerases • 從海底熱泉（hydrothermal vent）所分離 的微生物生成耐熱的DNA polymerases（ Table 14. 3） • 用在分子生物研究上，如Polymerase Chain Reaction(PCR) • 2015年就有380億美元市場，第一個是從 Thermus aquatics所分離，稱為Taq polymerase • 有其他high fidelity（高忠實）的酵素

Some DNA polymerases 95 C半衰期 (min) Proofreading 修正功能 40 Thermus aquaticus 陸地 陸地 40 - Vent Thermococcus litoralis 海底熱泉 400 ＋ Deep Vent Pyrococcus 海底熱泉 1380 ＋ Tth Thermus thermosphilus 陸地 20 - Pfu Pyrococcus furiosus 120 ULTm Thermotoga maritimea 海底熱泉等 海底熱泉 ＋ ＋ 酵素名 生物 來源 Taq Thermus aquaticus Amplitaq 50

海洋微生物polymers的應用 • 欲於復育、 業製程、生產、食品加 等 • Bioadhesives – https: //en. wikipedia. org/wiki/Bioadhesive • 水底coating，如船底降低draging • Dyes and Sunscreen • Poly-hydroxy-ß-hydroxyalkanoates（ PHA）作為biodegradable plastics

Sunscreen products • From cyanobacteria – UV absorbing pigments – Scytonemin – Shinorine • 篩選 – http: //link. springer. com/article/10. 1007%2 Fs 12275009 -0118 -6

Bioactive Pigments from Marine Bacteria • http: //www. hindawi. com/journals/ecam/2 011/670349/

Poly-hydroxy-ß-hydroxyalkanoates（ PHA） • Biodegradable plastics • Linear polyesters produced in nature by bacterial fermentation of sugar or lipid • https: //en. wikipedia. org/wiki/Polyhydroxy alkanoates • Ralstonia eutropha and Alcaligenes spp. , Pseudomonas putida, Aeromonas hydrophila, Thiococcus pfennigii等