PLANTS PLANTS Phytotoxicology Active Principle CASTOR Botanical Name
PLANTS
PLANTS • Phytotoxicology • Active Principle
CASTOR • Botanical Name Ricinus Communis • Common Name Castor, Arand
CASTOR • Active Principle Ricin (toxalbumin)
CASTOR • Uses Purgative Lubricant
CASTOR • Fatal Dose 5 -10 raw seeds 1 mg/kg of Ricin • Fatal Period 2 -7 days
CASTOR Clinical Features 1) GIT irritation 2) Renal 3) Skin
CASTOR Management 1) 2) 3) 4) 5) Removal of Unabsorbed poison Decrease the absorption Increase the excretion Antidote Symptomatic
CASTOR Autopsy Findings 1) 2) 3) 4) Mucosal inflammation Mucosal hemorrhage Crushed seeds in stomach Hemorrhages in organs
CROTON • Botanical Name Croton Tiglium • Common Name Croton, Jamalgota
CROTON • Active Principle Crotin (toxalbumin)
CROTON • Fatal Dose 4 -5 raw seeds • Fatal Period 4 -6 hours
CROTON Clinical Features 1) GIT irritation 2) Renal 3) Skin
CROTON Management 1) 2) 3) 4) 5) Removal of Unabsorbed poison Decrease the absorption Increase the excretion Antidote Symptomatic
CROTON Autopsy Findings 1) 2) 3) 4) Mucosal inflammation Mucosal hemorrhage Crushed seeds in stomach Hemorrhages in organs
ABRUS • Botanical Name Abrus Precatorius • Common Name Rati, Rosary Pea
ABRUS • Active Principle Abrin (toxalbumin)
ABRUS • Fatal Dose 1 -2 raw seeds 90 -120 mg Abrin • Fatal Period 3 -5 days
ABRUS Clinical Features 1) GIT irritation 2) Renal 3) Skin 4) Eyes
ABRUS Management 1) 2) 3) 4) 5) Removal of Unabsorbed poison Decrease the absorption Increase the excretion Antidote Symptomatic
ABRUS Autopsy Findings 1) 2) 3) 4) Mucosal inflammation Mucosal hemorrhage Crushed seeds in stomach Hemorrhages in organs
CAPSICUM • Botanical Name Capsicum Annum • Common Name Chili, Mirch
CAPSICUM • Active Principle Capsaicin
CAPSICUM Clinical Features 1) GIT irritation 2) Respiration 3) Skin 4) Eyes
MARKING NUT • Botanical Name Semicarpus Anacardium • Common Name Marking nut, Bhilawa
MARKING NUT • Active Principle Semecarpol Bhilawanol
MARKING ABRUSNUT • Fatal Dose 5 -8 raw seeds 10 gm. marking nut juice • Fatal Period 12 -24 hours
MARKING ABRUSNUT Clinical Features 1) GIT irritation 2) Skin (Artificial bruise)
MARKING ABRUSNUT Management 1) 2) 3) 4) 5) Removal of Unabsorbed poison Decrease the absorption Increase the excretion Antidote Symptomatic
MARKING ABRUSNUT Autopsy Findings 1) 2) 3) 4) Mucosal inflammation Oral cavity blisters Crushed seeds in stomach Hemorrhages in organs
MADAR • Botanical Name Calotropis Gigantea • Common Name Madar, Akdo
CROTON MADAR • Active Principle Calotropin Calotoxin Uscharin
CROTON MADAR • Fatal Dose Uncertain • Fatal Period 12 -24 hours
MADAR CROTON Clinical Features 1) GIT irritation 2) Renal 3) Skin
MADAR CROTON Management 1) 2) 3) 4) 5) Removal of Unabsorbed poison Decrease the absorption Increase the excretion Antidote Symptomatic
CROTON MADAR Autopsy Findings 1) 2) 3) 4) Mucosal inflammation Mucosal hemorrhage Crushed seeds in stomach Hemorrhages in organs
ERGOT • Botanical Name Claviceps Purpurea (a parasitic fungus)
CROTON MADAR ERGOT • Active Principle Ergotamine Ergotoxin Ergometrine
CROTON ERGOT MADAR • Fatal Dose 1 gm. Or more • Fatal Period 24 hours-several days
MADAR ERGOT CROTON Clinical Features 1) ACUTE POISONING(Rare) • GIT • Neuromuscular System
MADAR ERGOT CROTON Clinical Features 1) CHRONIC POISONING ERGOTISM St. Anthony’s Fire • Convulsive form • Gangrenous form
MADAR ERGOT CROTON Management 1) Removal of Unabsorbed poison 2) Symptomatic IV Nitroglycerine or Nitroprusside Oral Prazocin, Captopril, Nifedipine
CROTON MADAR ERGOT Autopsy Findings 1) 2) 3) 4) Mucosal inflammation Mucosal hemorrhage Particles in stomach Gangrene of toes
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