PICO Patient Severe sepsisSeptic shock Intervention source control

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PICO Patient: Severe sepsisもしくはSeptic shockの患者 Intervention: 抗生剤、source controlまでの時間 推奨が守られているか Comparison: なし Outcome: 28日死亡率

PICO Patient: Severe sepsisもしくはSeptic shockの患者 Intervention: 抗生剤、source controlまでの時間 推奨が守られているか Comparison: なし Outcome: 28日死亡率

Methods ドイツの４４施設における前向き縦断観察研究 敗血症患者の初期診療を行っており、 quality improvement processを参加している施設 ICUがない施設は除外 regional and national research and quality improvement

Methods ドイツの４４施設における前向き縦断観察研究 敗血症患者の初期診療を行っており、 quality improvement processを参加している施設 ICUがない施設は除外 regional and national research and quality improvement networkにて募集

ATまでの時間は長い傾向 ↓ 28日生存では有意差なし (ICU、院内生存率ではあり) German recommendation Compliant VS non-compliant 28日死亡率 34. 9% VS 34.

ATまでの時間は長い傾向 ↓ 28日生存では有意差なし (ICU、院内生存率ではあり) German recommendation Compliant VS non-compliant 28日死亡率 34. 9% VS 34. 3%(p=0. 869) Source control 十分VS不十分 26. 7％ VS 65. 6％(p=0. 001) (28日死亡率)

5日以内にescalate: 41. 9% 9. 5%で 5日以内にde-escalation De-escalation ありなしで 28日死亡率 22. 9%VS 36. 0%(p=0. 01)

5日以内にescalate: 41. 9% 9. 5%で 5日以内にde-escalation De-escalation ありなしで 28日死亡率 22. 9%VS 36. 0%(p=0. 01) AT時間 1時間以内でも 1時間以上でも、 Adequate VS inadequateで 有意差あり

PICO Patient Severe sepsisSeptic shock Intervention source controlPICO Patient Severe sepsisSeptic shock Intervention source control
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Chapter 13 Shock Defining Shock Shock is bestChapter 13 Shock Defining Shock Shock is best
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SHOCK SHOCK Se conoce como shock a laSHOCK SHOCK Se conoce como shock a la
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