Physiology in your Future Revised abstract due Friday

Physiology in your Future • Revised abstract due Friday at start of Class • Test # 3: 35% Hemorrhage Diagram – 30% Short Answer and 35% Multiple Choice – Check Moodle Wednesday afternoon for update on grades • Lab this week: Urinalysis 16/18; 16/20; 9/20; ? /14 • Looking over old tests – One opportunity only: Friday 2 -5 in the Pit – No paper, no pencils…. Just look over. • Exam Schedule and Sign-up on Friday

Exam Schedule • • • Monday morning, Olin Theater Monday afternoon, The Pit Tuesday afternoon, TBA Wednesday morning, The Pit Friday morning, The Pit Sign-up on Friday, no changes allowed. Studying for the Final Exam link from Lab website.

Course Evaluations and Surveys • Bio 342 for Wofford • CURE for Departmental Assessment – Look for link in upcoming email

S 20 The nephron

S 21 Fig. 14. 03 a

Fig. 14. 05 Glomerular Filtration Rate is 120 ml/min = 180 L/day Three stimuli for secretion of renin from JGC

Ultrafiltrate of plasma enters Bowman’s. Figure space 14. 03 Composition same as plasma except no formed elements and no proteins and no substances bound to proteins

Starling Fig. 14. 08 Forces variable

What substances can cause this constriction? Ways to alter GFR Fig. 14. 09 What happens during hemorrhage?

Board Diagram: cross section of tubule and peritubular capillary showing modes of transport for reabsorption and secretion.

Membrane proteins are segregated into apical (luminal) and basolateral membranes. Figure 14. 10 Amino acid e c r e t i o n S reabsorption metabolism glucose

Reabsorption and secretion in proximal tubule is NOT under hormonal control. Primary active transport of Na+ establishes a gradient for reabsorption of glucose, amino acids, etc. Reabsorption and secretion in DCT & CCD is under hormonal control. Hormones that act here: ANH, ADH, Aldosterone. Here, reabsorption of Na+ is linked to the secretion of K+.

Effect of ADH: insertion of more aquaporins in th the membranes Effect: Increase H 2 O reabsorption

Normally, all 14. 31 filtered Figure bicarbonate is “reabsorbed”