Phoenix Arizona October 3 2006 ASSOCIATION OF INDEPENDENT

Phoenix Arizona October 3, 2006 ASSOCIATION OF INDEPENDENT RESEARCH INSTITUTES PRESENTATION 1

FY 2007 ESTIMATE TOTAL NIH BUDGET AUTHORITY $28. 578 Billion Training 2. 7% $760. 5 Million Research Project Grants 52. 9% $15. 122 Billion 2

NIH BUDGET AUTHORITY FY 1977 – FY 2007 (Current vs. Constant 1977 Dollars Using BRDPI as the Inflation Factor) (Dollars in Billions) $30 $25 $20 $15 $10 $5 $0 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1979 1978 1977 Current Dollars Constant Dollars 3

CHANGE IN NIH APPROPRIATIONS FY 1995 - 2007 4

NIH RESEARCH GRANTS FISCAL YEARS 1950 – 2005 Current Dollars Constant Dollars, FY 1950 = 100. 0 5

NIH EXTRAMURAL AWARDS BY ACTIVITY FISCAL YEARS 1995 AND 2005 6

NIH AWARDS BY KIND OF INSTITUTION FISCAL YEARS 1995, 1999 AND 2005 7

NIH SUPPORT TO AIRI MEMBERS FISCAL YEARS 1995 – 2005 Current Dollars Constant Dollars 1995 = 100. 0 8

NIH Support to AIRI Members Fiscal Years 1995, 2000 and 2005 9

NIH EXTRAMURAL SUPPORT TO AIRI MEMBERS BY GRANT ACTIVITY FY 1995 FY 2000 FY 2005 10

NIH AWARDS TO AIRI MEMBERS BY SUPPORTING INSTITUTE FY 2005 11

NIH AWARDS TO AIRI MEMBERS BY SUPPORTING INSTITUTE FY 2005 12

NIH TRAINING AND CAREER DEVELOPMENT AWARDS 13

NIH R 01 EQUIVALENT COMPETING APPLICATIONS BY FISCAL YEAR OF REVIEW Originals Amendments 14

SUCCESS RATES FOR NIH COMPETING R 01 EQUIVALENT APPLICATIONS Original Applications Amendments 15

SUCCESS RATES FOR NIH COMPETING R 01 EQUIVALENT APPLICATIONS Original Applications Amendments 16

PERCENT OF R 01 EQUIVALENT APPLICATIONS FUNDED Based on type and IRG Action of original (Non-Amendment) 17

NIH COMPETING R 01 EQUIVALENT APPLICATIONS BY YEAR OF REVIEW 18

NIH COMPETING R 01, R 29 AND R 37 APPLICATIONS Amendments as percent of All Applications 19

NIH TRADITIONAL (R 01, R 29 AND R 37) RESEARCH PROJECT APPLICATIONS 20

SUCCESS RATES OF NIH COMPETING R 01 EQUIVALENT APPLICATIONS 21

NIH Support Of First Time Investigators 22

AVERAGE OF COMPETING R 01 EQUIVALENT AWARDEES 23

AVERAGE AT TIME OF FIRST ASSISTANT PROFESSORSHIP AT US MEDICAL SCHOOLS AAMC Faculty Roster Data 42 41 40 39 38 37 36 MD/Ph. D MD 35 34 33 32 1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 24

DISTRIBUTION OF INVESTIGATOR AGES 25

SUCCESS RATES BY AGE OF APPLICANT NIH R 01 EQUIVALENT APPLICATIONS 26

NIH TRADITIONAL (R 01, R 29 AND R 37) RESEARCH PROJECTS FY 2005 Average Budgeted Direct Cost 27

NIH TRADITIONAL RESEARCH PROJECTS (R 01, R 29 AND R 37) AVERAGE TOTAL COSTS 28

INDIRECT COST (F&A) AS A PERCENT OF TOTAL COST 29

TOTAL AWARDS RECEIVED BY AIRI MEMBERS 30

IN SUMMARY 31

THANK YOU 32