Peptide H 2 NTyrAlaCys GlyCOOH Peptide amino groupNterminalN

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Peptide 的表示法: H 2 N-Tyr-Ala-Cys. Gly-COOH Peptide中第一個胺基酸具有一個自由 的胺基(amino group)，又稱Nterminal(N-端)，最後一個胺基酸具有 一個自由的羧基(carboxyl group)稱Cterminal(C-端)。

Peptide 的表示法: H 2 N-Tyr-Ala-Cys. Gly-COOH Peptide中第一個胺基酸具有一個自由 的胺基(amino group)，又稱Nterminal(N-端)，最後一個胺基酸具有 一個自由的羧基(carboxyl group)稱Cterminal(C-端)。

GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRRT GDVFKGKRIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRRT GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRRT GSAKKGATLFKTRCLQCHTVEXGGPHKVGPNLHGIFGRHS GDVAKGEAAFKR-CSACHAIGESAKNKVGPQLNGIIGRTA 1 Human, 2 Chimpanzee, 3 Spider monkey, 4 Zebra,

GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRRT GDVFKGKRIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRRT GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRRT GSAKKGATLFKTRCLQCHTVEXGGPHKVGPNLHGIFGRHS GDVAKGEAAFKR-CSACHAIGESAKNKVGPQLNGIIGRTA 1 Human, 2 Chimpanzee, 3 Spider monkey, 4 Zebra, 5 Yeast, 6 Agrobacterium Cytochrome C(about 85 a. a. )

圖 5. 24 Anfinsen實驗

圖 5. 24 Anfinsen實驗

2, 3, Bisphoglycerate(BPG)在調節 hemoglobin的功能上扮演重要的角色。 缺乏BPG時，hemoglobin對氧有非常 高的親合力，當H+與CO 2增加時BPG結 合hemoglobin有助於穩定去氧的 hemoglobin(deoxy. Hb)。

2, 3, Bisphoglycerate(BPG)在調節 hemoglobin的功能上扮演重要的角色。 缺乏BPG時，hemoglobin對氧有非常 高的親合力，當H+與CO 2增加時BPG結 合hemoglobin有助於穩定去氧的 hemoglobin(deoxy. Hb)。

蛋白質技術 分離技術 管柱層析(column chromatography) 1分子篩層析法(gel filtration) 2離子交換層析法(ion exchanger) 3 HPLC 4親和性管柱

蛋白質技術 分離技術 管柱層析(column chromatography) 1分子篩層析法(gel filtration) 2離子交換層析法(ion exchanger) 3 HPLC 4親和性管柱

Methods for determining the threedimensional structure X-ray diffraction of a protein

Methods for determining the threedimensional structure X-ray diffraction of a protein

Globular proteins of tertiary have a variety structures Heme

Globular proteins of tertiary have a variety structures Heme

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