Pentose Phosphate Pathway Phosphoribosyl Pyrophosphate PRPP Amidophosphoribosyltransferase commitment

Pentose Phosphate Pathway Phosphoribosyl Pyrophosphate (PRPP) Amidophosphoribosyltransferase (commitment step) 5 -phosphoribosylamine Complex Pathway IMP dehydrogenase Inosine Xanthosine Monophosphate (XMP) GMP synthase Adenylosuccinate synthase Adenylo- Monophosphate (IMP) succinate Adenylosuccinate GMP AMP lyase reductase deaminase Guanine Adenine Nucleotidase Inosine Purine Guanase Nucleosidase/Phosph orylase Xanthine Hypo. Xanthine Uric Acid Xanthine oxido- xanthine oxoreductase

AMP deaminase: Missing EC 3. 5. 4. 6, an adenosine monophosphate deaminase. Both JGI and Manatee call an adenosine deaminase with EC 3. 5. 4. Guanase: Missing EC 3. 5. 4. 3, a guanine deaminase. RAST calls a hypothetical protein with EC 3. 5. 4. 3 AT THE EXACT SAME BASE PAIRS that JGI and Manatee called an adenosine deaminase. Xanthine oxidoreductase: Missing EC 1. 17. 3. 2 or 1. 17. 1. 4. Xanthine oxoreductase: Same EC numbers as Xanthine Oxidoreductase OVERARCHING QUESTIONS: Is it an adenosine monophosphate deaminase or a guanine deaminase? What is xanthine and why does our organism appear to have no ability to do anything with it (same with other halophiles)?

BLAST Result for adenosine / guanine deaminase: Most were cytidine deaminases… But the second highest result was a guanine deaminase! Conclusion: Possibly a guanine deaminase?