Pedigree Charts The family tree of genetics Pedigree
- Slides: 21
Pedigree Charts The family tree of genetics
Pedigree Charts I II III
Overview What is a pedigree? I. a. b. Definition Uses Constructing a pedigree II. a. b. III. Symbols Connecting the symbols Interpreting a pedigree
What is a Pedigree? u. A pedigree is a chart of the genetic history of family over several generations. u Scientists or a genetic counselor would find out about your family history and make this chart to analyze.
Constructing a Pedigree u Femal e u Male
Connecting Pedigree Symbols Examples of connected symbols: u. Fraternal twins u. Identical twins
Connecting Pedigree Symbols Examples of connected symbols: u. Couple u. Siblings
Example u What like? does a pedigree chart look
Symbols in a Pedigree Chart u Affected u X-linked u Autosomal carrier u Deceased
Interpreting a Pedigree Chart 1. Determine if the pedigree chart shows an autosomal or X-linked disease. – If most of the males in the pedigree are affected the disorder is X-linked – If it is a 50/50 ratio between men and women the disorder is autosomal.
Example of Pedigree Charts u Is it Autosomal or X-linked?
Answer u Autosomal
Interpreting a Pedigree Chart 2. Determine whether the disorder is dominant or recessive. – If the disorder is dominant, one of the parents must have the disorder. – If the disorder is recessive, neither parent has to have the disorder because they can be heterozygous.
Example of Pedigree Charts u Dominant or Recessive?
Answer u Dominant
Example of Pedigree Charts u Dominant or Recessive?
Answer u Recessive
Summary u Pedigrees are family trees that explain your genetic history. u Pedigrees are used to find out the probability of a child having a disorder in a particular family. u To begin to interpret a pedigree, determine if the disease or condition is autosomal or X-linked and dominant or recessive.
Pedigree Chart -Cystic Fibrosis
Down Syndrome= 3 of #21
Klinefelter’s = XXY
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