Pattern of somatic mutations in patients with Waldenstrm

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Pattern of somatic mutations in patients with Waldenström macroglobulinemia or Ig. M monoclonal gammopathy

Pattern of somatic mutations in patients with Waldenström macroglobulinemia or Ig. M monoclonal gammopathy of undetermined significance by Marzia Varettoni, Silvia Zibellini, Irene Defrancesco, Virginia Valeria Ferretti, Ettore Rizzo, Luca Malcovati, Anna Gallì, Matteo Giovanni Della Porta, Emanuela Boveri, Luca Arcaini, Chiara Candido, Marco Paulli, and Mario Cazzola haematol Volume 102(12): 2077 -2085 November 30, 2017 © 2017 by Ferrata Storti Foundation

MYD 88 allele burden in patients with Ig. M monoclonal gammopathy of undetermined significance,

MYD 88 allele burden in patients with Ig. M monoclonal gammopathy of undetermined significance, asymptomatic and symptomatic Waldenström macroglobulinemia. Marzia Varettoni et al. Haematologica 2017; 102: 2077 -2085 © 2017 by Ferrata Storti Foundation

Correlation of MYD 88 allele burden with disease phenotype in patients with Waldenström macroglobulinemia.

Correlation of MYD 88 allele burden with disease phenotype in patients with Waldenström macroglobulinemia. Marzia Varettoni et al. Haematologica 2017; 102: 2077 -2085 © 2017 by Ferrata Storti Foundation

Treatment-free survival of asymptomatic patients with Waldenström macroglobulinemia according to CXCR 4 mutation status.

Treatment-free survival of asymptomatic patients with Waldenström macroglobulinemia according to CXCR 4 mutation status. Marzia Varettoni et al. Haematologica 2017; 102: 2077 -2085 © 2017 by Ferrata Storti Foundation

Treatment-free survival of asymptomatic patients with Waldenström macroglobulinemia according to MYD 88 and CXCR

Treatment-free survival of asymptomatic patients with Waldenström macroglobulinemia according to MYD 88 and CXCR 4 mutational status. Marzia Varettoni et al. Haematologica 2017; 102: 2077 -2085 © 2017 by Ferrata Storti Foundation

Pattern of mutations observed in patients with (A) Ig. M monoclonal gammopathy of undetermined

Pattern of mutations observed in patients with (A) Ig. M monoclonal gammopathy of undetermined significance or (B) Waldenström macroglobulinemia. Marzia Varettoni et al. Haematologica 2017; 102: 2077 -2085 © 2017 by Ferrata Storti Foundation

Variant allele frequency of MYD 88 and CXCR 4 mutations as determined by next-generation

Variant allele frequency of MYD 88 and CXCR 4 mutations as determined by next-generation sequencing. Marzia Varettoni et al. Haematologica 2017; 102: 2077 -2085 © 2017 by Ferrata Storti Foundation

Variant allele frequency of MYD 88 and KMT 2 D mutations as determined by

Variant allele frequency of MYD 88 and KMT 2 D mutations as determined by next-generation sequencing. Marzia Varettoni et al. Haematologica 2017; 102: 2077 -2085 © 2017 by Ferrata Storti Foundation

Pattern of somatic mutations in patients with WaldenstrmPattern of somatic mutations in patients with Waldenstrm
MUTATION SPONTANEOUS MUTATIONS INDUCED MUTATIONS MUTATIONS Mutations areMUTATION SPONTANEOUS MUTATIONS INDUCED MUTATIONS MUTATIONS Mutations are
Mutations Mutations overview Smallscale mutations Missense mutations NonsenseMutations Mutations overview Smallscale mutations Missense mutations Nonsense
Mutations Mutations Types of Mutations Point Mutations occursMutations Mutations Types of Mutations Point Mutations occurs
Mutations 1 Base Mutations 2 Chromosomal Mutations WhatMutations 1 Base Mutations 2 Chromosomal Mutations What
Mutations AP Biology Mutations n Point mutations singleMutations AP Biology Mutations n Point mutations single
Mutations 1 Base Mutations 2 Chromosomal Mutations WhatMutations 1 Base Mutations 2 Chromosomal Mutations What