Pathology Visions Conference Digital Pathology HCIT Visions A

Pathology Visions Conference Digital Pathology HCIT Visions – A GE Healthcare Perspective Giri Iyer General Manager, Strategic Development Integrated IT Solutions 10/22/2007

A Tale of Two Cities… Patient Safety: Need better Tox data earlier Drug Efficacy: Need better biomarkers and ADME profiles Pre-Clinical Research Drug Candidate Funnel weak Drug Costs and Failure Rates Lost in Translation: Need better data exchange earlier Clinical Trial Process Patient Safety : Five Rights Checking Drug Efficacy: Need better drugs Clinical Care Delivery 3 GE Healthcare IITS July 24, 2007

The Future of Anatomical Pathology From Glass From Quasi-quantitative From Single Biomarker From Dx To Digital To Dynamic Range To Multiplexing To enabling Rx 4 GE Healthcare IITS July 24, 2007

Market Adoption Projection Market Access • Scan times • Image Quality • Latency • FDA approval • Workflow • Algorithms • Workflow • ROI story • TCO story Rx adopting first; AMCs for Research only Ref Labs driving clinical; AMCs for Clinical Main stream clinical adoption 2008 -2009 -2010+ Time 5 GE Healthcare IITS July 24, 2007

Key Drivers for Industry Success • Whole slide Imaging today. . In vivo molecular imaging tomorrow • Better standards for Interoperability…DICOM, Jpeg, HL 7, CDISC, MIMIx? , MIAPE? • FDA compliance vs speed-to-market trade-offs • Better Data Exchange…Fusion between Medical Informatics and Bio Informatics • Ultimate litmus test is Drug Efficacy that is concomitant with Patient Safety 6 GE Healthcare IITS July 24, 2007

GE HCIT Perspective • Industry evolution driven through image digitization • When its about fast scan times and high resolution images. . GE is a usual suspect • Industry definitions changing? P Is it a PACS? P Is it a LIS? P Is it just the old Anatomic Pathology Module on new steroids? • Interoperability with existing systems is key to success • Customer acceptance will depend upon transforming Pathology workflow with significant value added • Thanks for having us here. . The youngest start-up in the market… much to learn 7 GE Healthcare IITS July 24, 2007