Pandemic Influenza Preparedness Framework The PIP Framework and

Pandemic Influenza Preparedness Framework The PIP Framework and Partnership Contribution Implementation Third Annual SARInet Meeting, May 9 -11, 2016, Puerto Rico

What is PIP? ➔ Landmark, innovative public health arrangement to increase global preparedness to respond to pandemic influenza ➔ Focus is on increasing equity of access to life saving measures Member States Civil society organizations WHO ➔ Brings together Member States, industry, other key stakeholders, and WHO Industry © World Health Organization 2015 Other key stakeholders 2

Objectives of PIP Framework ➔ Two objectives to be pursued on an equal footing: − Improve sharing of influenza viruses with the potential to cause a pandemic among humans − Achieve more predictable, efficient, and equitable access to benefits arising from the sharing of viruses, notably vaccines and antiviral medicines © World Health Organization 2015 3

Key documents for the PIP Framework © World Health Organization 2014 4

From detection to protection…. across 5 AOW © World Health Organization 2014 5

© World Health Organization 2014 6

Total L&S (RO+HQ) Activity Work Plan Budget (2014 -15): % L&S Financial Implementation Rate $ 17, 597, 013 87% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Ø L&S receives 70% of preparedness funds Ø Programmatic implementation monitored across 6 Regional Offices and WHO HQ Ø 43 low income countries across all 6 WHO Regions receive PC funds to improve pandemic preparedness Ø 21 Indicators are used to show results across 4 critical functions for pandemic preparedness: Improve ability to detect, monitor, share novel influenza viruses and to sustain these capacities Ø Data are collected every 6 months. Three collections have been made for target countries, a baseline and two additional measurements. 7

Detection Monitoring Sharing Algorithm for laboratory detection of unusual influenza viruses National surveillance for ILI Reporting lab Country Implementation surveillance data to WHO Plan through Flu. Net and/or regional databases Registration in IRR or receiving kits from WHO CCs National surveillance for SARI Reporting epidemiologic Rapid Response Team surveillance data to WHO Training through Flu. ID and/or regional databases PCR Testing Integration of lab and Epi Shipping capacity data PCR Quality for non. Regular influenza seasonal influenza viruses surveillance reports Sharing samples with WHO CCs PCR Quality for seasonal influenza viruses Sharing sequence data Coordination at the Human Animal Interface Sustaining activities Evidence of sustainability National Influenza Centre Status Sequencing National “Early Warning” systems or Event Based Surveillance (EBS) © World Health Organization 2014 8

• At round 2, all regions showed improvements across the 4 critical functions for pandemic preparedness compared to the baseline • Latest round of data collection (round 3) was mid-March 2016. 9

Global level indicators: WHO Global Influenza Programme 140 120 100 80 60 40 20 0 EQAP 100% Sharing virus in past 2 years Global Indicators Baseline Reporting epi data Reporting virological data Global Indicators status © World Health Organization 2014 10

Output Indicators for AMRO priority countries Bolivia, Chile, Costa Rica, Dominican Republic, Ecuador, Haiti, Nicaragua and Suriname Baseline Target Status 8 0 Detection capacity # of countries with an established and functioning event based surveillance 0 system Monitoring capacity # of countries able to consistently report and analyse virological data 7 8 7 # of countries able to consistently report and analyse epidemiological data 0 8 4 Sharing Capacity # of countries sharing influenza virus with WHO CCs, H 5 Reference Laboratories and Essential Regulatory Laboratories at least once a year in the past two years NA NA 6 © World Health Organization 2014 11

AMRO Detection Capacity ➔ Event-based surveillance has been identified as a gap in target countries in the region ➔ PIP PC funds supported trainings in EBS for influenza and data management in the region in 2015 ➔ We expect to see an increase in country capacity for detection in the next round of data collection as a result of this investment. © World Health Organization 2014 12

AMRO Monitoring Capacity ➔ The interactive PAHO Flu. ID web-site launched in 2015 and allows transparent access to monitoring and surveillance data ➔ Bolivia, Chile, Costa Rica and Ecuador report full capacity for surveillance of patients hospitalized with severe acute respiratory illness (SARI) with samples routinely tested for influenza ➔ PIP PC funds are supporting a landscape analysis of activities being done to improve human-animal interface surveillance in the region © World Health Organization 2014 13

AMRO Sharing Capacity ➔ AMRO/PAHO has enhanced reporting of Epi and virological data to PAHO Flu. ID to allow real-time monitoring of influenza spread ➔ Chile, Ecuador and Suriname reported for the first time to Flu. ID ➔ 783 virus (seasonal and no-seasonal) samples sent to WHO CC ➔ Training of 50 laboratory technicians on sample conservation and timely submission to WHO CC to improve sample submission © World Health Organization 2014 14

AMRO Sustaining Capacity ➔ Chile, Costa Rica, Ecuador and Nicaragua all have NICs ➔ Most countries have established country plans for sustaining laboratory and surveillance activities ➔ New country plans reported for Costa Rica, Ecuador and Suriname in March 2015 © World Health Organization 2014 15

Summary points for your consideration ➔ Please ensure timely virus sharing − GISRS and NICs are a key part of the worlds defence against influenza − A key link in the chain from detection to prevention is timely virus sharing ➔Funds for capacity building are linked to results − PIP will continue to be a reliable stream of funding for capacity building …… but it is important to show progress © World Health Organization 2014 16

Act local – think global ➔ You are part of global team which requires action at and communication between all parts of the whole……. Target beneficiary (the citizen) Health provider Donors Ministry of Health/NIC WHO HQ WHO CO and RO ➔ Congratulations on your efforts so far, keep up the excellent work © World Health Organization 2014 17

World Health Organization 20 Avenue Appia 1211 Geneva 27 Switzerland PIP Framework Secretariat Pandemic and Epidemic Diseases Health Security email pipframework@who. int http: //www. who. int/influenza/pip/en/ Thank you �� Merci Cпасибо ﺷﻜﺮ Gracias