PAIN AND SUFFERING Scientific Philosophical and Religious Perspectives

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PAIN AND SUFFERING Scientific, Philosophical, and Religious Perspectives December 1, 2012

PAIN AND SUFFERING Scientific, Philosophical, and Religious Perspectives December 1, 2012

FICTION OR FACT? ?

FICTION OR FACT? ?

HYMENOPTERA – PARASITIC WASPS

HYMENOPTERA – PARASITIC WASPS

WHAT IS LIFE? Characteristics of Life (Biological) • Organization (cellular) • Reproduction • Responsiveness

WHAT IS LIFE? Characteristics of Life (Biological) • Organization (cellular) • Reproduction • Responsiveness • Evolution (continuous change) • Homeostasis (internal maintenance) • Energy Transformations

THERMODYNAMICS The study of energy transformations • First Law of Thermodynamcis (conservation of energy)

THERMODYNAMICS The study of energy transformations • First Law of Thermodynamcis (conservation of energy) • E = mc 2 is one expression of this • Second Law of Thermodynamics (disorder in a system) • Systems tend to proceed from ordered to disordered states • Free Energy changes in a reaction ( A + B → C + D ): G = H - T S • If G = 0, reaction is at equilibrium • If G < 0, reaction proceeds as written (spontaneous) • If G > 0, reaction will not proceed (non-spontaneous)

WHEN IS A REACTION SPONTANEOUS? EPotential Energy and Order (Entropy) High potential energy, more

WHEN IS A REACTION SPONTANEOUS? EPotential Energy and Order (Entropy) High potential energy, more order Low potential energy, less order Low potential energy

ATP HAS HIGH POTENTIAL ENERGY ATP consists of three phosphate groups, ribose, and adenine.

ATP HAS HIGH POTENTIAL ENERGY ATP consists of three phosphate groups, ribose, and adenine. Adenine Phosphate groups Ribose Energy is released when ATP is hydrolyzed. ATP Water ADP © 2011 Pearson Education, Inc. Inorganic phosphate Energy

EXERGONIC PHOSPHORYLATION REACTIONS er g (Lo ss on of P i ic fro m

EXERGONIC PHOSPHORYLATION REACTIONS er g (Lo ss on of P i ic fro m re er B ac ti AT n go A “Activated” substrate Ex ATP on P) ic d s in En ga (B A ti ac re Pi BPi Ex er g (B onic lo se reac tio s. P n i) on m fro P) AT AB ∆G Energy is required to synthesize AB Reactants • Products ATP is the energy currency of all living organisms © 2011 Pearson Education, Inc.

SOURCES OF ATP FOR LIVING CELLS • Autotrophs – can provide their own energy

SOURCES OF ATP FOR LIVING CELLS • Autotrophs – can provide their own energy • Phototrophs – light (plants) • Chemotrophs – inorganic chemicals (some microbes) • Heterotrophs – energy derived from organic molecules • All animals • Requires mechanisms for detection (sensory) and acquisition (eating) of food (organic molecules). © 2011 Pearson Education, Inc.

FOOD • Reduced organic compounds that can be harvested to provide chemical energy for

FOOD • Reduced organic compounds that can be harvested to provide chemical energy for ATP synthesis. Ø Herbivores Ø Carnivores Ø Omnivores • ALL require sensory systems for acquiring food. • Many require sensory systems for avoiding predation. © 2011 Pearson Education, Inc.

HOMEOSTASIS © 2011 Pearson Education, Inc.

HOMEOSTASIS © 2011 Pearson Education, Inc.

HOMEOSTATIC MECHANISMS • Thermoregulation (temperature) • Osmoregulation (electrolytes) • Nitrogen Balance (elimination of waste

HOMEOSTATIC MECHANISMS • Thermoregulation (temperature) • Osmoregulation (electrolytes) • Nitrogen Balance (elimination of waste products) • Oxygen levels • p. H balance (acidity) • Nutrient transport → ALL require energy (ATP) expenditure >>> evolutionary imperative for sensory development

EVOLUTION OF SENSORY MECHANISMS • Example, The Molluscan Eye

EVOLUTION OF SENSORY MECHANISMS • Example, The Molluscan Eye

EYE DIVERSITY

EYE DIVERSITY

VARIETY OF SENSORY RECEPTORS

VARIETY OF SENSORY RECEPTORS

NOCIRECEPTORS (PAIN)

NOCIRECEPTORS (PAIN)

EVOLUTION OF NERVOUS SYSTEMS

EVOLUTION OF NERVOUS SYSTEMS

PARENTAL INVESTMENT THEORY

PARENTAL INVESTMENT THEORY

PAIN AND SUFFERING (A REDUCTIONISTIC VIEW) • Thermodynamic need for energy to drive metabolic

PAIN AND SUFFERING (A REDUCTIONISTIC VIEW) • Thermodynamic need for energy to drive metabolic reactions and maintain homeostasis • Requires an interaction with the environment for detecting and acquiring food • Evolution of a variety of sensory receptors including for pain • Predator – prey relationships • Increasing complexity of integration centers (brain development) • Extended parenting time; emotional and social connections • Can be expanded to include suffering due to illness (genetic, infection, injury) >>>>>> Where is God in all this?

CHATECHISM OF THE CATHOLIC CHURCH • “The Church’ Magesterium, as authentic interpreter of the

CHATECHISM OF THE CATHOLIC CHURCH • “The Church’ Magesterium, as authentic interpreter of the affirmations of Scripture and Tradition, teaches that death entered the world on account of man’s sin” (CCC 1008) • “Illness and suffering have always been among the gravest problems confronted in human life. In illness, man experiences his powerlessness, his limitations and his finitude. Every illness can make us glimpse death. ” (CCC 1500) • “Illness can lead to anguish, self-absorption, sometimes even despair and revolt against God. It can also make a person more mature, helping him discern in his life what is not essential so that he can turn towards that which is. Very often illness provokes a search for God and a return to him. ” (CCC 1501) • “Christ’s compassion towards the sick and his many healings of every kind of infirmity are a resplendant sign that “God has visited his people” and that the Kingdom of God is close at hand. ” (CCC 1503) • “By his passion and death on the cross Christ has given new meaning to suffering: it can henceforth configure us to him and unite us with his redemptive Passion. ” (CCC 1505)

ONE REFLECTION • “Jesus promises us, over and over, that to follow him means

ONE REFLECTION • “Jesus promises us, over and over, that to follow him means taking the way of the cross. Why are we surprised then, when life is dark and painful? Why do we imagine God has abandoned us, or assume we’ve lost our way? Servants are not greater than their Master, Jesus tells us (Matt. 10: 24). If Jesus new hardship, rejection, betrayal, shame, and apparent failure, why do we expect our lot to be different? In our trials and troubles, we know the privilege of being united to Christ in his suffering. ” - Susan Pitchford, Give Us This Day, Nov. 28, 2012.

GOD AND MODERN BIOLOGY PROGRAM • Spring Schedule 2013 • Wed. , February 6,

GOD AND MODERN BIOLOGY PROGRAM • Spring Schedule 2013 • Wed. , February 6, 6 -9 PM John Haught book discussion (continued) • Sat. , March 2, time TBA Lecture/discussion with students – topic TBA • Thur. , April 4, 5 -9 PM An evening with John Haught; dinner and lecture event • Wed. , April 15, 7 PM Elizabeth Johnson lecture