OVULATION Ovulation It is the process of discharge

OVULATION

Ovulation It is the process of discharge of 2 ndary Oocyte along with cumulus oophorus cells into the peritoneal cavity by the rupture of wall of the mature graafian follicle and ovary at 14 ± 1 days before the onset of next menstruation. Arround middle of the cycle the ovarian follicle under the influence of FSH and LH, producing a cystic swelling or bulge on the surface of the ovary. A small avascular spot, the stigma soon appears on this swelling. Before ovulation, the secondary oocyte and some cells of the cumulus oophorus detach from the interior of the distended follicle.

Fig– showing the development of different growing follicles and discharge of 2 ndary oocyte with cumulus oophorus cells.

Ovulation usually follows the LH peak by 12 to 24 hours. The LH surge elicited by the high estrogen level in the blood, appears to cause the stigma. The stigma soon ruptures, expelling the secondary oocyte with the follicular fluid. The expelled secondary oocyte is surrounded by the zona pellucida and one or more layers of follicular cells, which are radially arranged as the corona radiata. The LH surge seems to induce resumption of the first meiotic division of the primary oocyte that’s why mature ovarian follicle contain secondary oocyte.

Showing Estrogen & LH Level during Ovulation

Fate of Ovulated Follicle

Relation of Ovulation with the Ovarian Cycle

Fate of Secondary Oocyte

Level of Pituitary hormones & Ovarian Hormones During Ovulation

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