Overview of the new phase of Barbara Mascialino

Overview of the new phase of Barbara Mascialino July 26 th 2004 July 26 th, 2004 Barbara Mascialino INFN-Genova

Introduction • First Phase already completed • Last March 19 th started the Second Phase. Its aim is to bring the requirements resulting from the General Study into an operative phase, developing a software system to fulfil them. July 26 th, 2004 Barbara Mascialino INFN-Genova

The simulation tool will be useful for space applications: - astronauts radioprotection, - airlines pilots radioprotection, - human presence in the space. HUMEX a study on the survivability and adaptation of humans to long-duration exploratory missions July 26 th, 2004 Barbara Mascialino INFN-Genova

Manyfold applications The outcome of the project would be relevant also for: • biological experiments • radiotherapy • radiobiology • physics (micro and nano-dosimetric studies) • technology transfer from the space environment to the society July 26 th, 2004 Barbara Mascialino INFN-Genova

Study plan • 1: study of the project environment • 2: creation of a application prototype • 3: development of the prototype and related components into an articulated application aimed at modelising the radiation effects at cellular and DNA levels. July 26 th, 2004 INFN-Genova

Software process guidelines • United Software Development Process – practical guidance and tools from the RUP – mapping onto ISO 15504 • Incremental and iterative life cycle model SPIRAL APPROACH The software will be devolped through a series of iterations, each one visiting all the main software disciplines July 26 th, 2004 Barbara Mascialino INFN-Genova

Deliverables ESA PSS-05 software development standard: - User Requirement Document - Software Specification Document - Software User Manual - Software Validation and Verification Plan July 26 th, 2004 INFN-Genova

Milestones PHASE 1 MILESTONE 1 SCIENTIFIC BACKGROUND PHASE 2 MILESTONE 2 USER REQUIREMENTS DOCUMENT PHASE 3 MILESTONE 3 PROTOTYPE PHASE 4 MILESTONE 4 SECOND ITERATION PHASE 5 MILESTONE 5 THIRD ITERATION July 26 th, 2004 INFN-Genova

Milestone 1: September 19 th 2004 Study of: - Space radiation environment - ESA space projects - Existing physics models - Radiation effects on macroscopic biological structures - Radiation effects on microscopic biological structures - Existing bio-chemical models - Existing Monte Carlo codes WORK TEAM DEFINITION July 26 th, 2004 INFN-Genova

Milestone 2: October 19 th 2004 - Review of functionality - Review and update of the User Requirement Document produced during the First Phase of the study July 26 th, 2004 INFN-Genova

Milestone 3: March 19 th 2006 First iteration: explorative prototype (verify capabilities to satisfy the User Requirements) - Update of the User Requirements - Study of the User Requirements - Design - Implementation - Test - Documentation July 26 th, 2004 INFN-Genova

Milestone 4: March 19 th 2007 Secon iteration: Modelisation of radiation interactions with macroscopic biological structures Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation Modelisation of radiation interactions with cellular structures Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation Modelisation of radiation interactions with microscopic biological structures Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation July 26 th, 2004 INFN-Genova

Milestone 5: March 19 th 2008 Third iteration: Modelisation of radiation interactions with macroscopic biological structures Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation Modelisation of radiation interactions with cellular structures Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation Modelisation of radiation interactions with microscopic biological structures Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation July 26 th, 2004 INFN-Genova

“Finally” Cellular specialisation? Cellular position? Cellular status? Oxigen component? July 26 th, 2004 INFN-Genova