Overview of PPR in West Africa Diallo Adama

Overview of PPR in West Africa Diallo Adama, CIRAD ECo-PPR - Epidemiology and Control of Peste des Petits Ruminants Inception Workshop for West Africa Ouagadougou, Burkina Faso, 25 -27 June 2019

Importance of Peste de Petits Ruminants Evolution of PPR Distribution in the world (2011) 1942 -1972 2007 1980 -1982 2008 1987 2009 -2011

World PPR GEOGRAPHICAL DISTRIBUTION Dr Adama Diallo: CIRAD, ISRA-LNERV, Dakar-Hann, Sénégal Adama. diallo@cirad. fr

4 Morbillivirus Genus

5 Molecular Epidemiology of PPR N gene-based Tree

N gene-based Tree

N gene-based Tree

Evolution in PPRV Lineage distribution IV III I II 8

Evolution in PPRV Lineage distribution IV III I II 9

Evolution in PPRV Lineage distribution IV III I II 10

PPRV Molecular Study in WA • David Shamaki: 1998. More than 200 samples were collected from different areas in Nigeria: lineage II

PPRV Molecular Study in WA • David Shamaki: 1998. More than 200 samples were collected from different areas in Nigeria: lineage II • Woma (2013): A total of 140 clinical samples from 16 sheep and 63 goats with symptoms suggestive of PPR were collected from different states of Nigeria during a four-year period (2010 -2013): lineage II and lineage IV • Salami (2010 -2014). More than 100 samples from Outbreaks attended in Senegal: lineage II • K. Tounkara (2014 -2017). 48/512 positifs collected in Mali: Lineage I, II and IV.

1 3 Monitoring of PPRV circulation West Africa

Monitoring of PPRV circulation NIGERIA 14

Map of West Africa showing sampling location according to their PPRV lineage II genetic cluster Closely related strains (same genetic cluster = same color in map) found in multiple West African countries Rond= échantillons séquencés pendant l’étude de Kadidia Carré = séquences disponibles sur Gen. Bank.

Evolution PPRV lineages distribution: West Africa SENEGAL NIGERIA BENIN Ghana 1969 - 1970 LINEAGE I 2010 LINEAGE II 1975 - 1995 LINEAGE II 2008 LINEAGE IV 1969 LINEAGE II 2011 LINEAGE II 1976 LINEAGE II 2010 LINEAGE II 16

Evolution in PPRV Lineage distribution Lineage II has evolved further in Western Africa, replacing Lineage IV has spread further from North to South IV III I II 17

PPRV Lineages Evolution in WA

PPRV LINEAGE DISTRIBUTION IN WA. 19

Livestock trade routes in West Africa

2 1 Livestock Mobility in WA

PPR-GCES

Approche par stades à l’échelon national Les stades correspondent à une combinaison de niveaux décroissants de risque épidémiologique et de niveaux croissants de prévention et de contrôle.

OIE PPR – Statut indemne: 56 pays + 1 zône

THANKS Protection Against PPR: PART of the Fight for Poverty Alleviation