OU Wa TER Prize Inaugural Winner Steve Luby

OU Wa. TER Prize Inaugural Winner: Steve Luby, MD Daniele Lantagne, PE Greg Allgood, Ph. D

Luby Resume • Trained as an Internal Medicine doctor • CDC (1990 -1993) – EIS Officer (North Carolina), Malaria Branch • Aga Khan University, Karachi (1993 -1998) – Professor of Epidemiology • CDC (1998 -2004) – Collaborative research with Procter & Gamble • ICDDR, B (2004 -) – $400, 000 in 2004 to $5. 2 million in 2007 • Published 140 peer-reviewed journals

Changing the Dominant Paradigm (% reduction in diarrhea) • • Hygiene (handwashing) Sanitation Water Supply Water Treatment 1992 2004 -33% -36% -19% -15% -42% -24% -23% -39%

Seminal Lancet Handwashing Study • Showing efficacy of handwashing – 53% reduction of diarrhea with plain soap – 50% reduction of pneumonia – 34% reduction of impetigo – No difference between plain and antibacterial soap • “Favourite paper” in Infectious Disease, 2005 Luby, S. P. et al. Effect of handwashing on child health: a randomised controlled trial. Lancet. 366 (9481): 225 -33 (2005).

Combined Interventions • Significant data on diarrheal disease reduction – Very little on combined interventions • Combining hypochlorite, Pu. R, handwashing (percent reduction in diarrheal disease) – – 55% in hypochlorite neighborhoods 51% in handwashing neighborhoods 64% in Pu. R neighborhoods 55% in Pu. R + handwashing neighborhoods “No benefit by combining”

Selected Research: Chulli Filter • Critical evaluation – 21% reported use – Cost, inconvenience, mechanical problems – Only 4/101 still using – Stored samples indicated recomtamination • “resolve before further implementation”

Summary • Steve is a: – Solid researcher who loves learning – Not afraid to publish unpopular data – Father, husband – Astounding mentor – A man who lives his work – Says “if you want peace, work for public health”