Organism Tissue Cell Organelle Molecules Physiology Physiome Modeling

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Organism Tissue Cell Organelle Molecules 개별 전체 Physiology Physiome Modeling Metabolism Metabolome -Stimulation Protein

Organism Tissue Cell Organelle Molecules 개별 전체 Physiology Physiome Modeling Metabolism Metabolome -Stimulation Protein Proteome Reconstitution m. RNA Transcriptome Holistic view Gene Genome “omics” Physiomics Metablomics Proteomics Transcriptomics Genomics

생명현상의 Overview : 생명현상의 분자기전 Information 생체정보 : hormone, cytokines, neurotransmitter→세포→유전 1 st messenger

생명현상의 Overview : 생명현상의 분자기전 Information 생체정보 : hormone, cytokines, neurotransmitter→세포→유전 1 st messenger O 2/영양분 cytokines neurotransmitters Hormones 당질 (당뇨병) 지질→저장 (비만, 동맥경화) -omics 2 nd messenger °Physiome ×Southern blot × Northern blot ×Genome=gene+chromosome -sequencing -SNP Western blot AAA Vt B TCA Protein (생리기능) Transcriptome: DNA chip m. RNA Vt C, E NADH themogenin ATP Cell homeostasis Proteome -2 D/Mass a. a 열 단백질 Maintenance E小 Hormesis Cell proliferation (replication) E多