Organism class existing FSN hierarchy designator omitted Organism

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Organism class (existing FSN – hierarchy designator omitted) Organism class (proposed term) Life cycle

Organism class (existing FSN – hierarchy designator omitted) Organism class (proposed term) Life cycle stage (defining class) Instance 19061001 | Ascaris lumbricoides Any / all / not specified The A lumbricoides parasitizing Fred. 699574003 | Ascaris lumbricoides egg Egg stage of Ascaris lumbricoides An A. lumbricoides egg retrieved from Fred, sitting on a microscope slide. 609064008 | Ascaris lumbricoides larval form Ascaris lumbricoides larva Larval stage of Ascaris lumbricoides An A. lumbricoides larva in Fred’s lung biopsy. 609046001 | Ascaris lumbricoides worm Ascaris lumbricoides adult Adult stage of Ascaris lumbricoides An adult A. lumbricoides living in Fred’s intestine. 66953006 | Ascaris Genus Ascaris Any / all / not specified The organisms parasitizing a particular patient.

Organism class (existing FSN – hierarchy designator omitted) Definition 19061001 Ascaris lumbricoides Class that

Organism class (existing FSN – hierarchy designator omitted) Definition 19061001 Ascaris lumbricoides Class that includes all organisms in any stage Value for “causative agent” role in logical definition of of their life cycle that bear an A. lumbricoides 50982003 | Infection by Ascaris lumbricoides (disorder). genome. 699574003 Ascaris lumbricoides egg An egg of A. lumbricoides Value recorded in/on a diagnostic report Egg stage of Ascaris lumbricoides A life cycle stage of A. lumbricoides. The eggs of this organism are produced in the GI tract of human beings. A. lumbricoides embryos develop during this stage. Eggs are ingested by the host (human being) and hatch to become A. lumbricoides larvae. Value for “participates in” role in logical definition of 699574003 | Ascaris lumbricoides egg 609064008 Ascaris lumbricoides larva A larva of A. lumbricoides Value recorded in/on a diagnostic report Larval stage of Ascaris lumbricoides A life cycle stage of A. lumbricoides. The larvae of this organism first migrate to the lungs where they molt, are coughed up and swallowed. These larvae mature in the GI tract of human beings. A. lumbricoides embryos develop during this stage. Use case Value for “participates in” role in logical definition of 609064008 | Ascaris lumbricoides larva

Organism class (existing FSN – hierarchy designator omitted) Definition Use case 609046001 Ascaris lumbricoides

Organism class (existing FSN – hierarchy designator omitted) Definition Use case 609046001 Ascaris lumbricoides adult An adult of the species A. lumbricoides Value recorded in/on a diagnostic report Adult stage of Ascaris lumbricoides A life cycle stage of A. lumbricoides. The adults of this organism live in the GI tract of human beings and reproduce sexually. The female lays eggs in the GI tract of human beings. This is the (human) parasitic stage. Value for “participates in” role in logical definition of 609064008 | Ascaris lumbricoides adult 66953006 | Ascaris Value in causative agent role for 2435008 | Ascariasis (disorder)

OBO v SNOMED CT organism class

OBO v SNOMED CT organism class

OBO v SNOMED CT Life-cycle stage class

OBO v SNOMED CT Life-cycle stage class

SNOMED CT version of the model

SNOMED CT version of the model

OMITTED VARIABLE BIAS Omitted variable bias Fundamentals ofOMITTED VARIABLE BIAS Omitted variable bias Fundamentals of
Memory Hierarchy memory hierarchy A memory hierarchy consistsMemory Hierarchy memory hierarchy A memory hierarchy consists
GENE organism 1 organism 2 GENE organism 1GENE organism 1 organism 2 GENE organism 1
Class class Class for Name Class Class classClass class Class for Name Class Class class
QM 222 Class 13 Section D 1 OmittedQM 222 Class 13 Section D 1 Omitted
QM 222 Class 19 Omitted Variable Bias ptQM 222 Class 19 Omitted Variable Bias pt