Optum Rx Smart Fill Program Smart Fill Overview

Optum. Rx Smart Fill Program

Smart Fill Overview Split Fill (1/2 Monthly Supply) 90 -Day Supply Oral Oncology HIV, MS, RA, Transplant Unstable on medication Stable on medication Clinical Intent Adjust to medication Adherence Program Intent Avoid waste Member convenience Increased clinical oversight Improved satisfaction 6 fills over first 3 months 4 fills over 12 months ½ copay 3 x copay No (mandatory) Yes (voluntary) Conditions/Drugs Patient Stability Member Experience # Fills/Duration Copays Opt in Program Offering Confidential property of Optum. Do not distribute or reproduce without express permission from Optum.

Smart Fill Optimizes Medication Fulfillment To The Clinical Needs Of The Member Split Fill Program 90 -Day Supply Program Certain conditions have serious side effects that may cause some members to discontinue use. Longer fills are good for members that have stable conditions and are well maintained on therapy. For the first three months: • ½ of regular prescribed supply limit • ½ of regular copay After 6 months of therapy: • 90 -day fill • 3 x copay 3

Split Fill – Oncology Medications: High Discontinuation Toxic Side Effects from Oral Oncology Medications Lead to High Discontinuation Rates. Standard Split Fill Drug List 49%* Impacted Oral Oncology Drugs Afinitor® Nexavar® Sprycel® Sutent® Tarceva® Discontinue therapy within 90 days Targretin® Tasigna® Votrient® Zolinza® Increased Waste of Medications. *Based on UHC and Optum. Rx member population. Confidential property of Optum. Do not distribute or reproduce without express permission from Optum. 4

Oral Oncology Split Fill Program Waste Avoidance Through Filling 2 x per Month. Split Fill Program • Two fills per month • Prorated copay Current Fulfillment • One fill per month Potential for early discontinuation due to intolerance • • Side effects impact adherence Member stops taking medication Remaining drug on hand is wasted Increased patient engagement • • • More frequent touch points (2 x/ month) Education Adherence monitoring Early identification of adverse events Regular patient/provider communication Reduced drug waste and realization of accompanying savings Confidential property of Optum. Do not distribute or reproduce without express permission from Optum. 5

90 Day Supply Member Experience 90 -Day Fill Members adherent for six months are given option to receive 90 -day supply Member Outreach Member Chooses 90 -day Member Declines 90 -day Care coordinator contacts every three months Care coordinator contacts once per month Screen for adherence Confidential property of Optum. Do not distribute or reproduce without express permission from Optum.