Onepoint arterial blood sampling at 10 min 123
One-point arterial blood sampling at 10 min 123 I-IMP (167 MBq) IV injection Lung dynamic image for 5 min Brain SPECT for 30 min (6× 5 min) CT FIGURE 1. Outlines of the procedures of 123 I-IMP data acquisition with gamma camera by the method shown in this study.
18000 16000 14000 Counts 12000 10000 8000 UCL 6000 4000 2000 0 0 Lung dynamic image ( 0 -5 min after IMP injection ) 100 Time 200 5 (min) 300 400 Time-activity curve FIGURE 2. The area under the time-activity curve of the lungs (UCL)
Estimated Ca 10 (cps/g) 2000 n = 99 y = 0. 7469 x + 255. 82 r = 0. 77 (p<0. 01) 1600 1200 800 400 800 1200 1600 Measured Ca 10 (cps/g) 2000 FIGURE 3. Comparison between the estimated Ca 10 and the directly measured Ca 10 in the total 99 patients.
Mean CBF value calculated using the estimated Ca 10 (ml/min/ 100 g) (A) 80 60 40 n = 29 y = 1. 0842 x + 4. 69 r = 0. 795 20 0 0 20 40 60 80 Mean CBF value calculated using the measured Ca 10 (ml/min/100 g) FIGURE 4 -A. Comparison between the mean CBF values calculated using the estimated Ca 10 and those calculated using the directly measured Ca 10 in patients with Parkinson’s disease.
Mean CBF value calculated using the estimated Ca 10 (ml/min/ 100 g) (B) 80 60 n = 32 y = 0. 8445 x + 5. 84 r = 0. 784 40 20 0 0 20 40 60 80 Mean CBF value calculated using the measured Ca 10 (ml/min/100 g) FIGURE 4 -B. Comparison between the mean CBF values calculated using the estimated Ca 10 and those calculated using the directly measured Ca 10 in patients with common or internal carotid artery occlusion or stenosis.
Mean CBF value calculated using the estimated Ca 10 (ml/min/ 100 g) (C) 80 60 n = 14 y = 0. 6016 x + 12. 687 r = 0. 624 40 20 0 0 20 40 60 80 Mean CBF value calculated using the measured Ca 10 (ml/min/100 g) FIGURE 4 -C. Comparison between the mean CBF values calculated using the estimated Ca 10 and those calculated using the directly measured Ca 10 in patients with moya disease.
Mean CBF value calculated using the estimated Ca 10 (ml/min/100 g) (D) 80 60 n = 12 y = 0. 8126 x + 6. 79 r = 0. 771 40 20 0 0 20 40 60 80 Mean CBF value calculated using the measured Ca 10 (ml/min/100 g) FIGURE 4 -D. Comparison between the mean CBF values calculated using the estimated Ca 10 and those calculated using the directly measured Ca 10 in patients with cerebral infarction
Mean CBF value calculated using the estimated Ca 10 (ml/min/ 100 g) (E) 80 60 n = 12 y = 0. 6842 x + 7. 63 r = 0. 854 40 20 0 0 20 40 60 80 Mean CBF value calculated using the measured Ca 10 (ml/min/100 g) FIGURE 4 -E. Comparison between the mean CBF values calculated using the estimated Ca 10 and those calculated using the directly measured Ca 10 in patients with the other diseases.
Mean CBF value calculated using the estimated Ca 10 (ml/min/ 100 g) (F) 80 60 n = 99 y = 0. 8957 x + 2. 80 r = 0. 785 40 20 0 0 20 40 60 80 Mean CBF value calculated using the measured Ca 10 (ml/min/100 g) FIGURE 4 -F. Comparison between the mean CBF values calculated using the estimated Ca 10 and those calculated using the directly measured Ca 10 in the total 99 patients.
(A) Parkinson’s Disease 72 yo, Male (B) Rt. - ICA Stenosis 68 yo, Male (C) Moyamoya Disease 40 yo, Male (D) Cerebral Infarction(Lt. MCA) 60 yo, Male Figure 5.
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