OHC inhibition and excitation OHCs model OHC models

OHC inhibition and excitation

OHC’s model

(OHC model’s equation (1 }

OHC Properties

Linear Approximation

(OHC model’s equation (2 When:

The embedded model

Frequency Domain Model

Parameters Estimation For and

Model’s Simulation Relative • basilar membrane velocity

Cochlear representations of Chirp Cochlear representation

Cochlear representations of “SHEN” Cochlear representation

Model’s Simulation

Impaired Hearing

Simulated Audiograms Normal OHC activity Partial damaged OHC No OHC activity

Non Linear Properties 3/4/2021 10: 41 AM

Non Linearity

Postmortem Effect

Non Linear Properties

Non linearity and Cubic Combination Tones Compression – Output ‘Cochlear amplifier’ – many non-linear • effects Combination Tones – Input 2 f 1 -f 2 f 1 f 2 Frequency

Combination Tones- Psychophysics

Combination Tones – Basilar Membrane

CT with non linear functions All non linear functions types in all model • components can cause CT Time Frequency Input = 2 k. Hz + 2. 44 k. Hz; Equal level

Otoacoustic Emissions

The Human Ear Model Outer ear Middle ear TM Incudostapedial joint Oval window microphone Piston based model •

Middle ear model equations

Cochlear response to a click 100 us Stapes Stimulus Apex

Introducing cochlear “roughness”

Model Representation – click

Emission Spectrum

Simulated Audiograms Normal OHC activity with “roughness” Partial OHC activity with “roughness”

Damaged cochlear response