Occupational skin diseases Dr Omid Aminian Occupational Dermatoses

Occupational Dermatoses • Occupational association first made by Ramazzini • Percival Pott occupational induced

Work place agents that induced skin disorder n Chemicals Acids Alkalis Solvents Oils Detergents

Important causal agents of occupational skin illness n Machinery n Metal products n Electronic

Occupational dermatoses n n Occupational injuries Laceration & Puncture %81 Chemical & Thermal burn

Occupational Dermatoses • Seven common conditions 1. irritant contact dermatitis 2. 3. 4. 5.

Contact Dermatitis n 90% of skin lesions seen in work placep 80% -- irritant

Irritant Contact Dermatitis n Erythema to eczematous changes to papules, vesicles n Caused by

Skin disease and possible etiologies n Ulceration strong acids (HF-H 2 SO 4) strong

OCCUPATIONAL HISTORY 1. 2. 3. 4. 5. Description of all job Work exposure Timing

PREVENTION 1. 2. 3. 4. 5. 6. 7. Hazards identification Engineering controls Chemicals substitution

AGENTS ASSOCIATED WITH DERMAL INJURIES AGENT APPLICATION THERAPY ALKALI Cement cleaners Water irrigation CHROMC

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Occupational skin diseases Dr Omid Aminian

Occupational Dermatoses • Occupational association first made by Ramazzini • Percival Pott occupational induced cancer of the scrotum in chimney sweeps in 1775 • 25% of work-related illness

Work place agents that induced skin disorder n Chemicals Acids Alkalis Solvents Oils Detergents Resins Plastics Metals Petroleum product Plant & wood n Physicals Temperature Ionizing radiation Non ionizing radiation n Biologic Viruses (orf-wart-herpes) Bacteria (anthrax-erisopeloid) Fungi (candidadermatophyte) Parasites (scabies(schistosomiasis) n Mechanicals Pressure Friction Vibration

Important causal agents of occupational skin illness n Machinery n Metal products n Electronic equipment n Food products Cutting oils Solvents Metallic salts Solvents Plastic & resin Fruits & vegetables Soap & detergents n Agriculture n Health services Chemicals Fruits & nuts Soap & detergents Infectious agents

Occupational dermatoses n n Occupational injuries Laceration & Puncture %81 Chemical & Thermal burn Others %14 %5 Occupational Illness Contact dermatitis %90 Infectious diseases %5/5 Neoplasm & others %4/5

Occupational Dermatoses • Seven common conditions 1. irritant contact dermatitis 2. 3. 4. 5. 6. 7. allergic contact dermatitis photosensitive dermatitis pigment alterations acneiform conditions contact uticaria malignancies

Contact Dermatitis n 90% of skin lesions seen in work placep 80% -- irritant 20% -- allergic

Irritant Contact Dermatitis n Erythema to eczematous changes to papules, vesicles n Caused by chronic exposure to mild irritants Fissuring n Hyperpigmentation n Hardening

Skin disease and possible etiologies n Ulceration strong acids (HF-H 2 SO 4) strong alkali (Na. OH-KOH) solvent (acrylonitrile-CS 2 ) n Folliculitis& acne arsenic trioxide-glass fiber n Milia n Leukoderma occlusive dressing UV-IR phenol-cresol n Alopecia thallium-chloroprene n Urticaria cosmetics-plants n Granuloma silica-beryllium n Lichenoid p-phenylene diamine n Scleroderma vinyl chloride-silica PCB oil-

OCCUPATIONAL HISTORY 1. 2. 3. 4. 5. Description of all job Work exposure Timing of symptom Illness among other workers Non-work exposure

PREVENTION 1. 2. 3. 4. 5. 6. 7. Hazards identification Engineering controls Chemicals substitution Personal hygiene Personal protection gloves, barriercream, clothing Education & training Preemployment & periodic examination

AGENTS ASSOCIATED WITH DERMAL INJURIES AGENT APPLICATION THERAPY ALKALI Cement cleaners Water irrigation CHROMC electroplating Water irrigation ACID PHENOL HYDRO FLURIC ACID Ascorbic acid %10 pharmaceutic Saline al irrigation Poly ethylene glycol Glass etching Water irrigation Magnesium sulfate %25 Calcium gluconate%10